SENSORIMOTOR AND AUTONOMIC DYSREGULATION IN HEREDITARY SENSORY AND AUTONOMIC NEUROPATHIES
Funder
National Health and Medical Research Council
Funding Amount
$50,406.00
Summary
Specific genetic mutations can lead to widespread changes in the body. Here we are looking at the congenital Hereditary and Sensory Autonomic Neuropathies, the most common of which primarily affects Eastern European Jews. Affected individuals have difficulty walking and controlling their blood pressure, and also have an indifference to pain. This series of experiments aims to increase our understanding of the underlying neurophysiological disturbances.
How, What and Who in Human Communication: Movement of Face and Voice. The aim of this project is to identify the essential characteristics of tone, affect, and identity from face and voice using a combination of signal processing, biological, and behavioural techniques in order to develop a comprehensive model of auditory-visual speech processing and communication. This research will significantly improve understanding of the basis of auditory-visual perception and production in tonal languages ....How, What and Who in Human Communication: Movement of Face and Voice. The aim of this project is to identify the essential characteristics of tone, affect, and identity from face and voice using a combination of signal processing, biological, and behavioural techniques in order to develop a comprehensive model of auditory-visual speech processing and communication. This research will significantly improve understanding of the basis of auditory-visual perception and production in tonal languages and in affective communication, facilitate links between neurophysiological processes and auditory-visual speech processing; and contribute to applications in automatic person recognition, automatic speech recognition, text-to-speech systems, and talking head aids for the hearing impaired.Read moreRead less
Special Research Initiatives - Grant ID: SR0354596
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Perception and Action in Auditory Scenes (PAAS): Neural, Behavioural, Computational and Mechanical Systems. Auditory scenes are temporal and ephemeral yet pervasively influence human life. How humans negotiate such scenes has not been solved, a fact highlighted by attempts to build machines to respond to speech, warnings etc., in real-world situations with room reverberation, different talkers, and background noise. No one discipline can solve such problems. In this network outstanding researche ....Perception and Action in Auditory Scenes (PAAS): Neural, Behavioural, Computational and Mechanical Systems. Auditory scenes are temporal and ephemeral yet pervasively influence human life. How humans negotiate such scenes has not been solved, a fact highlighted by attempts to build machines to respond to speech, warnings etc., in real-world situations with room reverberation, different talkers, and background noise. No one discipline can solve such problems. In this network outstanding researchers from physical, medical, human, and social sciences with interests in speech, music and audition will provide insights into how humans and machines localize, recognize, interpret and produce auditory events, and advance frontier technologies, e.g., automatic speech recognition, hearing prostheses, auditory monitoring/warning systems.Read moreRead less
Filters reveal what flicker conceals: temporal processing in the human visual system. I have recently discovered a new form of camouflage using 10Hz luminance flicker. This project will quantify this effect and examine the extent to which it generalises across colour and spatial dimensions and to video sequences depicting natural scenes. This information is expected to provide foundational information to technologies relating to national security that rely on visual concealment. This research wi ....Filters reveal what flicker conceals: temporal processing in the human visual system. I have recently discovered a new form of camouflage using 10Hz luminance flicker. This project will quantify this effect and examine the extent to which it generalises across colour and spatial dimensions and to video sequences depicting natural scenes. This information is expected to provide foundational information to technologies relating to national security that rely on visual concealment. This research will examine the extent to which filtering out these camouflaging frequencies enhances our sensitivity to low temporal frequency information. This decamouflaging aspect of my research is expected to improve the clarity of digital video-based technologies including ultrasound, educational, info-tainment and defence applicationsRead moreRead less
Broadcasting 3D Audio: Recording, Transmission, and Playback. With the current state of the art, a performance at the Sydney Opera House cannot be recorded and broadcast such that you can listen to it as if you are in the best seat of the house. The goal of our project is to develop the ultimate form of multi-channel audio broadcasting to create this experience. We will develop and implement effective systems for recording, broadcasting and playback of 3D audio in three different scenarios: indi ....Broadcasting 3D Audio: Recording, Transmission, and Playback. With the current state of the art, a performance at the Sydney Opera House cannot be recorded and broadcast such that you can listen to it as if you are in the best seat of the house. The goal of our project is to develop the ultimate form of multi-channel audio broadcasting to create this experience. We will develop and implement effective systems for recording, broadcasting and playback of 3D audio in three different scenarios: individual headphone reproduction; small loudspeaker array reproduction; and large loudspeaker array reproduction. We will create optimal recording techniques and broadcasting software for each of these playback techniques.Read moreRead less
Discovery And Mechanisms Of Host Cell Factors In HIV Uncoating
Funder
National Health and Medical Research Council
Funding Amount
$635,098.00
Summary
HIV entry into the host cell involves release of its capsid, a protein shell protecting the viral genome. The capsid hijacks host proteins to cloak itself from cellular defenses while the cell has evolved sensors that can block viral infection. This proposal aims to discover proteins involved in this arms race between host and virus and decipher how they control capsid disassembly. This insight will help design new drugs against HIV infection and new ways to deliver genes for gene therapies.
The Role Of Corticothalamic Feedback On The Response Dynamics Of Thalamic Neurons
Funder
National Health and Medical Research Council
Funding Amount
$351,852.00
Summary
A fundamental question in neuroscience is how the brain selectively processes sensory information to generate a reliable representation of the world. Positioned in the centre of the brain, the thalamus plays a key role in sensory processing. This project investigates how the interaction between thalamus and cortex shapes the selection and gating of sensory information. This is a fundamental question in basic neuroscience with the potential to increase our knowledge about attentional deficits.
Temporal segmentation, leadership and cognition in musical improvisation and creativity. Improvisation is core to conversation and to creative and social emergence. This project investigates musical improvisation, in order to reveal constituent processes, using computational and cognitive approaches. Mechanisms for generating transitions in the temporal stream, and for asserting social power or position in it are assessed. Improvised material can be explored, modified, and developed in the creat ....Temporal segmentation, leadership and cognition in musical improvisation and creativity. Improvisation is core to conversation and to creative and social emergence. This project investigates musical improvisation, in order to reveal constituent processes, using computational and cognitive approaches. Mechanisms for generating transitions in the temporal stream, and for asserting social power or position in it are assessed. Improvised material can be explored, modified, and developed in the creative process, and the project investigates how this occurs and whether computers can facilitate the process. Such contributions can be critical to the development of innovation in research and cultural arenas in Australia. Read moreRead less
The effect of multisensory and sensory-motor training on auditory accommodation. Learning to use a hearing aid or cochlear implant requires the brain to make adaptive changes to the new type of sensory information provided to the ears. This project examines what drives this accommodation and how we may accelerate the process and maximise its benefits by training so that listeners are able to make better use of these devices.