Discovery Early Career Researcher Award - Grant ID: DE210100790
Funder
Australian Research Council
Funding Amount
$419,308.00
Summary
Understanding how the brain combines sensory information. The ease with which we perceive the external world belies the complexity involved in integrating different sensory inputs. How does the brain achieve this fundamental operation? The project will address this question using a multidisciplinary approach that combines computational modelling, brain imaging, and psychophysical techniques. The expected outcomes of the project are a better understanding of how people perceive the world through ....Understanding how the brain combines sensory information. The ease with which we perceive the external world belies the complexity involved in integrating different sensory inputs. How does the brain achieve this fundamental operation? The project will address this question using a multidisciplinary approach that combines computational modelling, brain imaging, and psychophysical techniques. The expected outcomes of the project are a better understanding of how people perceive the world through optimal integration of sensory cues. In addition to advancing basic scientific knowledge, the findings will illuminate perceptual anomalies in normally developing children and will provide a foundation for reducing a debilitating side effect of virtual reality systems known as ‘cybersickness’.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100508
Funder
Australian Research Council
Funding Amount
$462,948.00
Summary
How predictions affect visual processing across the cortical hierarchy . Unlike traditional theories of visual perception, recent evidence suggests what a person expects can fundamentally change how they see the world. However, the neuronal mechanisms which would allow expectation to affect perception are poorly understood. This project will use revolutionary recording techniques to determine how multiple brain regions interact to use predictions about the future to change visual processing. The ....How predictions affect visual processing across the cortical hierarchy . Unlike traditional theories of visual perception, recent evidence suggests what a person expects can fundamentally change how they see the world. However, the neuronal mechanisms which would allow expectation to affect perception are poorly understood. This project will use revolutionary recording techniques to determine how multiple brain regions interact to use predictions about the future to change visual processing. The expected outcome is understanding a fundamental theory of brain function for the first time at the level of single neurons. This project will contribute to a new understanding of central theories of how the brain allows us to see which will significantly enhance basic vision science.Read moreRead less
The rules governing combined rod and cone photoreceptor signalling in visual pathways. The research program investigates vision at dim (mesopic) light levels where rod and cone photoreceptors simultaneously transmit visual information. The interaction between rod and cone signals is not trivial because their different amplitudes, timings and delays significantly change the perceptual qualities of our visual experience. The research addresses fundamental questions about how the retina and brain i ....The rules governing combined rod and cone photoreceptor signalling in visual pathways. The research program investigates vision at dim (mesopic) light levels where rod and cone photoreceptors simultaneously transmit visual information. The interaction between rod and cone signals is not trivial because their different amplitudes, timings and delays significantly change the perceptual qualities of our visual experience. The research addresses fundamental questions about how the retina and brain integrate disparate signals from the rods and cones to produce a homogenous visual percept. New psychophysical and electroretinographic paradigms will independently control the retinal photoreceptors to resolve the long standing problem of how noise modifies signalling and information flow between the retina and visual cortex.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140101505
Funder
Australian Research Council
Funding Amount
$395,220.00
Summary
Visual computation in the primate brain: circuits for motion processing. This project will investigate the neural mechanism that mediates motion detection, a fundamental visual function. Although computational theories have been developed to explain how neurons can detect moving objects and patterns, it has been very difficult to investigate how (or if) the models are implemented in the visual cortex. This project will examine controversial aspects of current theories. Using innovative methods, ....Visual computation in the primate brain: circuits for motion processing. This project will investigate the neural mechanism that mediates motion detection, a fundamental visual function. Although computational theories have been developed to explain how neurons can detect moving objects and patterns, it has been very difficult to investigate how (or if) the models are implemented in the visual cortex. This project will examine controversial aspects of current theories. Using innovative methods, the project will characterise neurons connected in a motion detection circuit for the first time, as well as study how they function after a critical component in the circuit is shut off. The research will lead to a better understanding of how visual experience is created by the brain and will have implications in computer vision and bionics.Read moreRead less
The role of spike patterning in shaping human perception of tactile stimuli. Every touch sensation from our fingertips is conveyed to the brain through the nerves by means of electrical impulses similar to any digital device. Using unique technology developed in our lab we can intercept this neural communication and insert our own messages to test how these signals are interpreted and converted into perceptual experiences. We aim to reveal the rules by which timing of neural signal patterns shap ....The role of spike patterning in shaping human perception of tactile stimuli. Every touch sensation from our fingertips is conveyed to the brain through the nerves by means of electrical impulses similar to any digital device. Using unique technology developed in our lab we can intercept this neural communication and insert our own messages to test how these signals are interpreted and converted into perceptual experiences. We aim to reveal the rules by which timing of neural signal patterns shapes the perception of touch - specifically intensity and frequency of vibration. By recording signals from neurons and by testing human perception, we will learn about neural processing mechanisms. The new knowledge generated about sensory coding will be essential for rendering a virtual sense of touch.Read moreRead less
Adaptation and after effects in perception of tactile motion. This project investigates sensory properties of the skin covering the human hand, focusing on the ability to perceive how surfaces move across the palm when objects are handled or explored. This project aims to elucidate sensory information processing, leading to applications in diagnostics of neurological disorders and robotics.
Melanopsin function in humans. This project aims to understand melanopsin signalling in humans. A newly discovered retinal ganglion cell class expresses the melanopsin photopigment. Melanopsin signalling controls neural functions for light dependent image formation and non-image forming processes. Many of these are unknown in humans. This project will use a 5-primary photostimulator to define how melanopsin controls these processes in humans. The outcomes are expected to advance understanding of ....Melanopsin function in humans. This project aims to understand melanopsin signalling in humans. A newly discovered retinal ganglion cell class expresses the melanopsin photopigment. Melanopsin signalling controls neural functions for light dependent image formation and non-image forming processes. Many of these are unknown in humans. This project will use a 5-primary photostimulator to define how melanopsin controls these processes in humans. The outcomes are expected to advance understanding of human vision. This could provide avenues for using light to increase active participation in society and improve health and well-being, and strategies to assess human vision and the body’s internal clock.Read moreRead less
Vision and lighting in the age of melanopsin. This project aims to develop innovative new technologies, which will advance understanding of the effects of light on human behavior mediated via the recently discovered melanopsin photopigment in the eye. The project expects to create a cutting-edge visual display technology, which will deliver the foundation knowledge of melanopsin shapes visual perception. The project will redefine current knowledge of human vision and provide a practical lighting ....Vision and lighting in the age of melanopsin. This project aims to develop innovative new technologies, which will advance understanding of the effects of light on human behavior mediated via the recently discovered melanopsin photopigment in the eye. The project expects to create a cutting-edge visual display technology, which will deliver the foundation knowledge of melanopsin shapes visual perception. The project will redefine current knowledge of human vision and provide a practical lighting solution to suit the biological needs of humans, especially in relation to the human body’s internal (circadian) clock. Read moreRead less
Multimodal testing for a fast subcortical route for salient visual stimuli. This project aims to uncover links between underlying brain circuitry, uncertainty and consciousness, and perceptions of fear. The project will use a multi-modal combination of brain imaging and neural recording techniques to generate new knowledge about the brain’s processing of biologically relevant information. The expected outcomes will enhance our knowledge of how the brain rapidly and non-consciously prepares the ....Multimodal testing for a fast subcortical route for salient visual stimuli. This project aims to uncover links between underlying brain circuitry, uncertainty and consciousness, and perceptions of fear. The project will use a multi-modal combination of brain imaging and neural recording techniques to generate new knowledge about the brain’s processing of biologically relevant information. The expected outcomes will enhance our knowledge of how the brain rapidly and non-consciously prepares the body for potential escape behaviours and of the brain pathways engaged in fear perception. The outcomes have the potential to inform strategies for overcoming anxiety and its effects on daily life, social interactions and workplace productivity.Read moreRead less
The neural dynamics of real-time processing in the brain. The aim of this project is to investigate a new model for predictive coding of sensory processing in the brain in which the brain compensates for the time delays in neural transmission by maintaining a real-time temporal alignment of the neural activity. This results in a representation of sensory information that is aligned in time across the cortex, offering a new fundamental principle for how the brain functions in a highly dynamic wor ....The neural dynamics of real-time processing in the brain. The aim of this project is to investigate a new model for predictive coding of sensory processing in the brain in which the brain compensates for the time delays in neural transmission by maintaining a real-time temporal alignment of the neural activity. This results in a representation of sensory information that is aligned in time across the cortex, offering a new fundamental principle for how the brain functions in a highly dynamic world whose outcomes would provide a deeper understanding of brain function. It could also have profound significance for artificial intelligence and brain-inspired technologies, as well as benefit neural sensory prostheses and brain-machine interfaces.Read moreRead less