Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Probing the Tasmanian Devil Serum Proteome for Preclinical Diagnosis of Devil Facial Tumour Disease. The Tasmanian Devil (Sarcophilus harrisii) is a carnivorous marsupial endemic to the island state of Tasmania, and is found all over the state. Over the past decade, a dramatic decline has occurred in the Devil population in association with the emergence of Devil Facial Tumour Disease (DFTD). This project aims to develop a preclinical diagnostic test for DFTD that will provide vital information ....Probing the Tasmanian Devil Serum Proteome for Preclinical Diagnosis of Devil Facial Tumour Disease. The Tasmanian Devil (Sarcophilus harrisii) is a carnivorous marsupial endemic to the island state of Tasmania, and is found all over the state. Over the past decade, a dramatic decline has occurred in the Devil population in association with the emergence of Devil Facial Tumour Disease (DFTD). This project aims to develop a preclinical diagnostic test for DFTD that will provide vital information for use in developing management strategies to ensure the ongoing survival of the Tasmanian Devil. The benefit to Australia in performing this research rests in the new technology that will be developed and the application of this technology to key areas of national and international significance.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775621
Funder
Australian Research Council
Funding Amount
$494,000.00
Summary
Mileura Widefield Array: A New Low Frequency Telescope. A new radio-quiet site for international radio astronomy is being developed at Mileura in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addi ....Mileura Widefield Array: A New Low Frequency Telescope. A new radio-quiet site for international radio astronomy is being developed at Mileura in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addition, the telescope will measure the solar wind, and its potential interactions with the earth.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882938
Funder
Australian Research Council
Funding Amount
$1,430,000.00
Summary
MIRA Widefield Array: a new low frequency telescope. A new radio-quiet site for international radio astronomy is being developed at Boolardy in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In additi ....MIRA Widefield Array: a new low frequency telescope. A new radio-quiet site for international radio astronomy is being developed at Boolardy in Western Australia. We have constructed a low frequency test array on the site, and established that the site is excellent for radio astronomy. We plan to build a telescope which will observe the early universe, when stars and galaxies where first born. This will be the first telescope capable of this type of measurement of the early universe. In addition, the telescope will measure the solar wind, and its potential interactions with the Earth. Read moreRead less
Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia ....Modelling and control of mosquito-borne diseases in Darwin using long-term monitoring. Management of mosquito populations is a high public health priority because these insects can spread diseases such as malaria, dengue, Ross River virus, Barmah Forest virus, Murray Valley encephalitis, Japanese encephalitis and Kunjin/West Nile virus. Our research into the effectiveness of mosquito control programs in Darwin is of immediate national relevance and priority given the need to Safeguard Australia from invasive diseases. There is an urgency to undertake our research because global environmental change and increasing movements of people (particularly military personnel) from overseas regions where these diseases are endemic is increasing the vulnerability of northern Australia to the (re)establishment of mosquito borne diseases.Read moreRead less
Predicting the diagnostic performance of individuals and organisations. Predicting the diagnostic performance of individuals and organisations. This project aims to address diagnostic error in advanced technology systems, by providing a mechanism to assess and improve individual diagnosticians’ performance. Organisations that rely on their employees’ diagnostic skills rarely assess them once the operators become qualified, so there is no basis for interventions that might prevent diagnostic erro ....Predicting the diagnostic performance of individuals and organisations. Predicting the diagnostic performance of individuals and organisations. This project aims to address diagnostic error in advanced technology systems, by providing a mechanism to assess and improve individual diagnosticians’ performance. Organisations that rely on their employees’ diagnostic skills rarely assess them once the operators become qualified, so there is no basis for interventions that might prevent diagnostic errors affecting thousands. This research tests a new method of assessing diagnostic skills based on how skilled operators respond to cues. This project will test how employees’ diagnostic skills change and whether this change corresponds to measures of organisational performance. This research is expected to provide organisations with a tool to pre-empt diagnostic errors that could minimise costs to the economy.Read moreRead less
Ring constructions and algorithms for enhancing performance of BCH codes. BCH codes form a major class of codes used in modern communication systems. The aim of this project is to enhance the efficiency of this class of codes by combining them in constructions enabling correction of deletion and insertion errors, and develop efficient implementations of encoding and decoding algorithms incorporating soft decision methods for enhanced error correction. Significance of the project is explained by ....Ring constructions and algorithms for enhancing performance of BCH codes. BCH codes form a major class of codes used in modern communication systems. The aim of this project is to enhance the efficiency of this class of codes by combining them in constructions enabling correction of deletion and insertion errors, and develop efficient implementations of encoding and decoding algorithms incorporating soft decision methods for enhanced error correction. Significance of the project is explained by the role of fast, secure and reliable communications in modern information and communication technology. Expected outcomes include new efficient algorithms and commercial modules available for symbolic computation systems with applications in telecommunications industry.
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Improving Signal Detection Range of Active Seismic Monitoring in Mines. This project will develop a new generation of sensors that will process incoming seismic waves from an active source to accurately estimate the properties of underground rock mass in real time. This will lead to safer mining operations that will decrease the number of injuries and deaths. A probability graph model will be used to fuse measurements from different sensors to produce more accurate estimates of the rock mass. A ....Improving Signal Detection Range of Active Seismic Monitoring in Mines. This project will develop a new generation of sensors that will process incoming seismic waves from an active source to accurately estimate the properties of underground rock mass in real time. This will lead to safer mining operations that will decrease the number of injuries and deaths. A probability graph model will be used to fuse measurements from different sensors to produce more accurate estimates of the rock mass. A new low-cost seismic source will excite large areas of rock mass for continuous monitoring of the changes in stress and fracture density caused by mining. This will lead to methodologies that will significantly improve mining operations and increase Australia’s productivity in the mining sector.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100021
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre in Energy Technologies for Future Grids. The proposed Future Grids Training Centre will advance Australia’s transition to a clean energy future. It will address the complex and challenging issues currently limiting the growth of renewable energy through innovations that facilitate widespread integration of these resources into electricity grids while maintaining grid stability. The Centre will deliver the next generation of industry leaders and specialists in future grid tech ....ARC Training Centre in Energy Technologies for Future Grids. The proposed Future Grids Training Centre will advance Australia’s transition to a clean energy future. It will address the complex and challenging issues currently limiting the growth of renewable energy through innovations that facilitate widespread integration of these resources into electricity grids while maintaining grid stability. The Centre will deliver the next generation of industry leaders and specialists in future grid technologies for renewable energy generation, transmission and distribution, supported by renewable hydrogen energy storage and market driven customer responsiveness enabled by new information and communications technologies, to provide a more sustainable, reliable, secure and affordable electricity system.Read moreRead less