Discovery Early Career Researcher Award - Grant ID: DE170100398
Funder
Australian Research Council
Funding Amount
$410,507.00
Summary
How T cells modulate stem cells and tissue regeneration. The project aims to determine how T cells modulate tissue repair and regeneration in mammals. Most of the mechanisms modulating the healing of tissues are elusive. This research is expected to reveal unknown mechanisms controlling the processes of tissue repair and regeneration, particularly the nexus between the stem cells involved in the tissue healing process and the immune response .
Microscale microRNA Detection and Delivery for Effective Point-of-Care Cancer Screening and Therapeutics. MicroRNAs are short RNA molecules that play a critical regulatory role in gene expression. Recently discovered in 1993, microRNA research has since received considerable attention and is regarded as an emerging revolutionary frontier in medicine given its therapeutic ability to ‘turn off’ certain genes that lead to various diseases. Additionally, microRNA expression signatures are a strong b ....Microscale microRNA Detection and Delivery for Effective Point-of-Care Cancer Screening and Therapeutics. MicroRNAs are short RNA molecules that play a critical regulatory role in gene expression. Recently discovered in 1993, microRNA research has since received considerable attention and is regarded as an emerging revolutionary frontier in medicine given its therapeutic ability to ‘turn off’ certain genes that lead to various diseases. Additionally, microRNA expression signatures are a strong biomarker for many diseases such as cancer. This project will advance the chip-scale acoustic microcentrifugation and nebulisation technology we recently pioneered to overcome the significant hurdles currently faced in microRNA detection and delivery with the aim of developing prototype portable microdevices for early stage cancer screening and therapy.Read moreRead less