The Social Life of Death. This project aims to investigate experiences of death, dying and bereavement amidst rapid social, economic and political transformation. In the wake of COVID19, and as Australia’s anticipated ‘death boom’ approaches, how to foster good deaths has never been more uncertain, nor more urgent. Drawing on innovative methods and socio-cultural theory, and working in partnership with families and communities, this project aims to generate new knowledge to better inform and imp ....The Social Life of Death. This project aims to investigate experiences of death, dying and bereavement amidst rapid social, economic and political transformation. In the wake of COVID19, and as Australia’s anticipated ‘death boom’ approaches, how to foster good deaths has never been more uncertain, nor more urgent. Drawing on innovative methods and socio-cultural theory, and working in partnership with families and communities, this project aims to generate new knowledge to better inform and improve policy and spark cultural renewal around the end of life. Expected outcomes include setting the international benchmark for novel scholarly understandings of death, dying and bereavement, and centring community voices in addressing contemporary challenges to dying well.
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Enhancing sleep and wellbeing in working families. This project aims to investigate the role of sleep on individuals’ health by measuring Australians' sleep patterns relative to work and family demands. This project expects to generate new knowledge in the sociology of sleep using innovative data collection bringing together cross-national, nationally representative, longitudinal and physiological data on Australians’ sleep patterns. Expected outcomes of this project are to identify the social a ....Enhancing sleep and wellbeing in working families. This project aims to investigate the role of sleep on individuals’ health by measuring Australians' sleep patterns relative to work and family demands. This project expects to generate new knowledge in the sociology of sleep using innovative data collection bringing together cross-national, nationally representative, longitudinal and physiological data on Australians’ sleep patterns. Expected outcomes of this project are to identify the social and biological determinants of sleep and their links with health, family and economic policy recommendations.Read moreRead less
The sociology of antibiotics and the antimicrobial resistance crisis. This project aims to investigate the sociological dimensions of antibiotics consumption by examining the views and experiences of clinicians, decision-makers, and members of the general population. The project expects to generate new knowledge about the social aspects of antibiotics use and consumer-provider interactions. Expected outcomes of this project include stronger consumer-provider collaborations about antibiotic use a ....The sociology of antibiotics and the antimicrobial resistance crisis. This project aims to investigate the sociological dimensions of antibiotics consumption by examining the views and experiences of clinicians, decision-makers, and members of the general population. The project expects to generate new knowledge about the social aspects of antibiotics use and consumer-provider interactions. Expected outcomes of this project include stronger consumer-provider collaborations about antibiotic use and a new evidence-base to guide policy decisions. This project should provide significant benefits for the national response to antimicrobial resistance, including enhanced public education and public policy.Read moreRead less
From mainstream to margins: The denormalisation of underage heavy drinking. This mixed-methods study aims to investigate changes in, and contemporary experiences of, heavy drinking for underage young people in Australia. The project expects to generate new knowledge on whether and how processes of ‘de-normalisation’ are shaping heavy drinking practices and experiences of social inclusion for underage young people. Expected outcomes of the project include the development of a contemporary theoret ....From mainstream to margins: The denormalisation of underage heavy drinking. This mixed-methods study aims to investigate changes in, and contemporary experiences of, heavy drinking for underage young people in Australia. The project expects to generate new knowledge on whether and how processes of ‘de-normalisation’ are shaping heavy drinking practices and experiences of social inclusion for underage young people. Expected outcomes of the project include the development of a contemporary theoretical model of underage drinking. This should provide significant benefits such as advancing understanding of the social and structural factors shaping heavy underage drinking practices. Findings can be used to inform policy directions aiming to holistically maximise health and social wellbeing for young people.Read moreRead less
How does an essential histone variant effect changes in gene expression? The mechanisms that determine how genes are switched on and off in different tissues and at different times are not clearly known. It is well established that gene expression patterns are determined in part by the molecular signals transmitted by variation in the proteins that package eukaryotic DNA. Our aim is to understand new aspects of these mechanisms that revolve around how our DNA is packaged. This foundational knowl ....How does an essential histone variant effect changes in gene expression? The mechanisms that determine how genes are switched on and off in different tissues and at different times are not clearly known. It is well established that gene expression patterns are determined in part by the molecular signals transmitted by variation in the proteins that package eukaryotic DNA. Our aim is to understand new aspects of these mechanisms that revolve around how our DNA is packaged. This foundational knowledge will deepen our understanding of gene regulation in all complex organisms and will inform future efforts to rationally modulate gene expression patterns in agriculture, research and other important areas.Read moreRead less
Regulatory architecture of the trunk-to-tail transition. This project aims to elucidate gene regulatory mechanisms that control how the head-to-tail axis is laid down during embryonic development. The project capitalises on unique pluripotent stem cell resources and cutting-edge genomic technology developed by the team. This project expects to generate new knowledge in the area of developmental biology and gene regulation that is anticipated to have wider application to the understanding of evol ....Regulatory architecture of the trunk-to-tail transition. This project aims to elucidate gene regulatory mechanisms that control how the head-to-tail axis is laid down during embryonic development. The project capitalises on unique pluripotent stem cell resources and cutting-edge genomic technology developed by the team. This project expects to generate new knowledge in the area of developmental biology and gene regulation that is anticipated to have wider application to the understanding of evolutionary mechanisms and ultimately regenerative medicine.Read moreRead less
Sick, lonely and left behind? A sociological study of loneliness. Loneliness is a serious and rapidly growing social problem in Australia. Although the negative health effects and mounting healthcare costs of loneliness are known, effective responses to loneliness are not. Taking a sociological approach, this project aims to generate new knowledge about the experience and meanings of loneliness for people and communities, and the social factors implicated in the rise of loneliness in contemporar ....Sick, lonely and left behind? A sociological study of loneliness. Loneliness is a serious and rapidly growing social problem in Australia. Although the negative health effects and mounting healthcare costs of loneliness are known, effective responses to loneliness are not. Taking a sociological approach, this project aims to generate new knowledge about the experience and meanings of loneliness for people and communities, and the social factors implicated in the rise of loneliness in contemporary Australia. By focusing on loneliness in people with long-term health conditions, this knowledge will be used to develop policy and practice recommendations for the health- and community-care sectors in how to support people and communities experiencing loneliness.Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Deciphering the regulatory principles of metazoan development. This proposal aims to elucidate how regulatory elements in the genome, known as enhancers, determine the identity and function of animal tissues. Currently, it is believed that enhancers cannot be traced across evolutionarily distant animals. The project uses novel concepts, computational and molecular approaches to identify deeply conserved enhancers. It further dissects the mechanism of function by proteomics and high-throughput ge ....Deciphering the regulatory principles of metazoan development. This proposal aims to elucidate how regulatory elements in the genome, known as enhancers, determine the identity and function of animal tissues. Currently, it is believed that enhancers cannot be traced across evolutionarily distant animals. The project uses novel concepts, computational and molecular approaches to identify deeply conserved enhancers. It further dissects the mechanism of function by proteomics and high-throughput genomics. The expected outcomes will overturn our current view on enhancer evolution and reposition our understanding of how enhancers are functionally encoded in the genome. The work is an important contribution to understanding cellular complexity and species evolution with wide-ranging impact in genetics.Read moreRead less
Lived experiences of treatment for hepatitis C in Australia. This project aims to support uptake of new hepatitis C treatments. With the introduction of new treatments in 2016, the Australian Government adopted the WHO’s goal of eliminating the disease by 2030. While early treatment rates were high, they have since plateaued, with stigma and poor information considered key obstacles. This project will generate new knowledge on treatment decisions and experiences, using a proven qualitative metho ....Lived experiences of treatment for hepatitis C in Australia. This project aims to support uptake of new hepatitis C treatments. With the introduction of new treatments in 2016, the Australian Government adopted the WHO’s goal of eliminating the disease by 2030. While early treatment rates were high, they have since plateaued, with stigma and poor information considered key obstacles. This project will generate new knowledge on treatment decisions and experiences, using a proven qualitative methodology. In doing so, it will produce a website covering personal experiences of treatment, issues in treatment decision-making, and advice on enhancing life on treatment and after. It will tackle hepatitis C-related stigma, and inform and benefit potential treatment users, families and relevant professionals.
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