Involvement of the Human Retinal Endothelial Cell in Blinding Eye Disease. Endothelial cells line the blood vessels of the vascular networks that circulate blood through the tissues. The molecular constitution of each endothelial cell is different and specific to function, but may predispose to tissue-specific disease. Retinal endothelial cells ensure the nutrition and protection of a tissue critical to vision, but are key participants in retinal ischemic, inflammatory and infectious diseases th ....Involvement of the Human Retinal Endothelial Cell in Blinding Eye Disease. Endothelial cells line the blood vessels of the vascular networks that circulate blood through the tissues. The molecular constitution of each endothelial cell is different and specific to function, but may predispose to tissue-specific disease. Retinal endothelial cells ensure the nutrition and protection of a tissue critical to vision, but are key participants in retinal ischemic, inflammatory and infectious diseases that threaten vision. This project will investigate molecular activities of retinal endothelial cells that are relevant to retinal disease processes and explore future biological therapies directed against the human retinal endothelial cell that address efficacy and safety deficiencies of current treatments.Read moreRead less
Using language to predict cognitive outcomes in old age. This project aims to understand the relationship between linguistic complexity metrics and cognitive decline in old age. The project will test the hypothesis that high linguistic complexity scores reflect the ability to strategically optimise processing in the face of age-related reductions in processing capacity. By studying the relation between complexity scores and real-time information processing (measured via electroencephalography) a ....Using language to predict cognitive outcomes in old age. This project aims to understand the relationship between linguistic complexity metrics and cognitive decline in old age. The project will test the hypothesis that high linguistic complexity scores reflect the ability to strategically optimise processing in the face of age-related reductions in processing capacity. By studying the relation between complexity scores and real-time information processing (measured via electroencephalography) across the adult lifespan (20–80 years), this project will develop a simple and accurate marker of the individual balance between processing capacity and strategy. This project has the potential to increase quality of life for the elderly and reduce costs of age-related cognitive impairment.Read moreRead less
Multi-modal virtual microscopy for quantitative diagnostic pathology. This project will contribute to the next generation of virtual microscopy systems that provide innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of diagnostic pathology. These tools will especially contribute to the screening and diagnosis of cervical, lung and bladder cancer.
Continuously learning to see. The ultimate goal of computer vision is to make a machine able to understand the world through analysis of images or videos. The new machine learning techniques developed in this project will enable previously impossible methods of computer vision and help strengthen Australia's competitiveness in this important area.
The microbe factory: a novel approach to benign minerals processing. The purpose of this project is to reduce the environmental impact of current mining practices. The anticipated outcome of this project is the replacement of toxic chemicals used in the separation of minerals with the novel use of environmentally benign microbes.