A Randomised Controlled Trial Of Exercise Programs For Preventing Knee Injuries
Funder
National Health and Medical Research Council
Funding Amount
$1,160,491.00
Summary
The promotion of physical activity, either through organised sport or active recreation, is a key public health strategy in this country. However, there is a risk of injury during this participation and efforts need to be undertaken to reduce this risk so that spor is safe for all. Sports injury prevention efforts to date in Australia have been severely hampered by a lack of evidence supporting currently advocated countermeasures. This concern has been recognised by both the NHMRC and the Common ....The promotion of physical activity, either through organised sport or active recreation, is a key public health strategy in this country. However, there is a risk of injury during this participation and efforts need to be undertaken to reduce this risk so that spor is safe for all. Sports injury prevention efforts to date in Australia have been severely hampered by a lack of evidence supporting currently advocated countermeasures. This concern has been recognised by both the NHMRC and the Commonwealth Department of Health and Ageing. It is imperative that we formally evaluate the effectiveness of sports injury countermeasures in the context of broad community level participation in sport, in contrast to previous research focussed on professional sport, and begin to deliver the preventive measures to the community. Australian football is a popular sport throughout Australia and it is associated with more medically-treated injuries than any other sport. Knee injuries are particularly common and can have severe consequences. One of the most commonly recommended knee injury prevention strategies is a well-designed exercise training program. Despite their potential to significantly reduce injury rates, the effectiveness of exercise training programs to prevent knee injuries in football, and indeed in most other sports, has not previously been assessed but has been identified as a priority research area by the NHMRC. This project will determine the effectiveness of exercise training programs for preventing knee injuries in community-level football players by monitoring injury rates, player behaviours and player attitudes before and after the training programs are implemented.Read moreRead less
“The Aftershock” – Understanding The Impact Of Traumatic Brain Injury On Depression And Emotional Regulation.
Funder
National Health and Medical Research Council
Funding Amount
$678,771.00
Summary
The majority of people with a traumatic brain injury (TBI) experience problems with mood and emotional regulation. We will use imaging to measure brain changes from TBI, and link these to risk of depression, as well as behavioural and molecular alterations. Study cohorts will include former international footballers, junior sports people and emergency patients presenting with an acute TBI. The project will inform current policy and provide a strong scientific basis for future work.
Does Manipulation Of Arterial Shear Stress Enhance Cerebrovascular Function And Cognition In The Aging Brain?
Funder
National Health and Medical Research Council
Funding Amount
$707,914.00
Summary
Globally, 9.2 million less cases of dementia could result from delaying it by as little as 12 months. We will assess the impact, on artery health and cognition, of a novel exercise intervention involving enhanced patterns of brain blood flow and arterial shear stress during exercise, stimuli which should optimise cerebrovascular health. Given that pharmacological approaches to prevention are ineffective, this project has the potential to address the future impact of this common and debilitating ....Globally, 9.2 million less cases of dementia could result from delaying it by as little as 12 months. We will assess the impact, on artery health and cognition, of a novel exercise intervention involving enhanced patterns of brain blood flow and arterial shear stress during exercise, stimuli which should optimise cerebrovascular health. Given that pharmacological approaches to prevention are ineffective, this project has the potential to address the future impact of this common and debilitating disease in Australians.Read moreRead less
Atrial Remodelling And Risk Of Arrhythmias In Endurance Athletes
Funder
National Health and Medical Research Council
Funding Amount
$1,006,750.00
Summary
Atrial fibrillation (AF) is a heart rhythm problem that is 3 to 5 times more common in male athletes than the general male population - the reasons for this excess are not known. We hypothesize that the cardiac enlargement that is caused by high intensity exercise training increases the risk of AF. We will assess heart structure and function in 420 athletes across the age spectrum and assess the degree to which sports-induced changes are permanent and whether this represents an AF risk.
International Orthopaedic Multicenter Study In Fracture Care (INORMUS)
Funder
National Health and Medical Research Council
Funding Amount
$1,462,437.00
Summary
INORMUS is a global multi-centre prospective cohort study in 40,000 patients with musculoskeletal trauma (e.g. fractures or dislocations) to determine the incidence of major trauma complications (i.e. mortality, re-operations, and infections) and to examine a number of factors that may predict early complications. This study will allow us to address fundamental questions for the millions of adults worldwide who experience trauma annually and will have immense public health implications.
Immediate Cooling And Emergency Decompression (ICED) For The Treatment Of Spinal Cord Injury: Pilot, Safety And Feasibility Studies
Funder
National Health and Medical Research Council
Funding Amount
$600,008.00
Summary
Victims of Spinal Cord Injury are young, have severe paralysis, complex needs and high lifetime costs. Although urgent surgery greatly improves outcome, it is difficult to achieve because of logistical difficulties. To expand the time window for early surgery, it is proposed to immediately cool patients. This project will conduct the pilot studies necessary before commencing a clinical trial of immediate cooling and emergency decompression (ICED) in patients with cervical spinal cord injuries.
Work-related Road Traffic Injury: Managing The Risk
Funder
National Health and Medical Research Council
Funding Amount
$508,943.00
Summary
Almost one third of registered motor vehicles in Australia are used for work purposes, the implications of this research namely, estimating the magnitude and identifying organisational determinants associated with work-related road traffic injury are substantial. Interventions arising from the findings of this research will contribute significantly to reductions in work-related road traffic injury and will support the National Road Safety Strategy target of a 30% reduction in serious injuries by ....Almost one third of registered motor vehicles in Australia are used for work purposes, the implications of this research namely, estimating the magnitude and identifying organisational determinants associated with work-related road traffic injury are substantial. Interventions arising from the findings of this research will contribute significantly to reductions in work-related road traffic injury and will support the National Road Safety Strategy target of a 30% reduction in serious injuries by 2030.Read moreRead less
The Transition From Hospital To Home: A Longitudinal Study Of Indigenous Traumatic Brain Injury (TBI)
Funder
National Health and Medical Research Council
Funding Amount
$888,851.00
Summary
The six-month transition period following discharge from hospital after a traumatic brain injury (TBI) is critical. During the transition period, key sentinel events may influence health and wellbeing. The research will investigate key sentinel events during the transition period following TBI in the first longitudinal study with Indigenous Australians. This study will provide the first systematic evidence regarding the support Indigenous Australians need to successfully transition back into the
Improving The Measurement Of Non-fatal Injury Burden - Validating The Global Burden Of Disease (GBD) Project Through Synthesis And Analysis Of The Six Leading Injury Outcome Cohort Studies From Around The World
Funder
National Health and Medical Research Council
Funding Amount
$155,443.00
Summary
This project will use data from the six largest and most comprehensive cohort studies across five countries to evaluate methods for determining the disability associated with injury. The findings will direct how injury burden is measured for by the Global Burden of Disease (GBD) Study, and for individual country or region-specific studies. The research will have direct relevance to Australia by improving outcome measurement in ways that are critical for enhanced clinical, public health policy an ....This project will use data from the six largest and most comprehensive cohort studies across five countries to evaluate methods for determining the disability associated with injury. The findings will direct how injury burden is measured for by the Global Burden of Disease (GBD) Study, and for individual country or region-specific studies. The research will have direct relevance to Australia by improving outcome measurement in ways that are critical for enhanced clinical, public health policy and planning settings.Read moreRead less
Paediatric Validating Injury Burden Estimates Study (VIBES-Junior)
Funder
National Health and Medical Research Council
Funding Amount
$484,562.00
Summary
Injury is a leading cause of death and disability in children and adolescents, and can have lifelong effects for survivors. This study will quantify how well children recover from injury, and how long this takes, to establish better measures of the population impact of injury sustained in childhood and adolescence. The findings will be used to inform future health and social policy concerning primary prevention of injury in childhood and adolescence and the provision of services after injury.