Development of the PD GeneChip: a research and diagnostic tool for Parkinson's disease. The PD GeneChip will provide both social and economic benefits to Australia. It will be a key research platform for Australian scientists, and will facilitate collaboration both within Australia and overseas. It will assist with health care management of PD (Parkinson's disease) patients by providing a cost-effective diagnostic tool and the possibility of predicting the clinical course of disease. This inform ....Development of the PD GeneChip: a research and diagnostic tool for Parkinson's disease. The PD GeneChip will provide both social and economic benefits to Australia. It will be a key research platform for Australian scientists, and will facilitate collaboration both within Australia and overseas. It will assist with health care management of PD (Parkinson's disease) patients by providing a cost-effective diagnostic tool and the possibility of predicting the clinical course of disease. This information will provide the basis for tailoring treatment to a patients needs. It is anticipated that marketing of the PD GeneChip within Australia and overseas may produce revenue of at least $40 million annually.Read moreRead less
Performance of safety critical anchors in early age concrete with SCM. This project aims to examine the performance of anchors in a range of cements, to contribute to new safety and building guidelines. Demands for faster construction cycles and increased productivity require anchors for lifting and joining concrete elements to be installed and loaded in early age concrete. Yet, best practice for evaluation of anchors is based on mature concrete. There is also increasing use of supplementary cem ....Performance of safety critical anchors in early age concrete with SCM. This project aims to examine the performance of anchors in a range of cements, to contribute to new safety and building guidelines. Demands for faster construction cycles and increased productivity require anchors for lifting and joining concrete elements to be installed and loaded in early age concrete. Yet, best practice for evaluation of anchors is based on mature concrete. There is also increasing use of supplementary cementitious materials with unknown effects on anchors. This project aims to address this construction industry challenge. The project plans to study experimentally and analytically the effect of early age creep on anchor installation and the factors affecting the slip behaviour and ultimate performance of cast-in and post-installed mechanical anchors in concretes. It is intended that these studies will then inform new design guidelines.Read moreRead less
Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
A new approach to structural design that incorporates the effect of non-structural components. The construction industry is a significant contributor to the Australian economy. Each year billions of dollars are spent erecting new high rise buildings. Further, Australian engineering firms bid on major construction projects throughout the world, particularly in Asia and the Middle East. The research described here promises to deliver economies to the Australian construction industry as well as e ....A new approach to structural design that incorporates the effect of non-structural components. The construction industry is a significant contributor to the Australian economy. Each year billions of dollars are spent erecting new high rise buildings. Further, Australian engineering firms bid on major construction projects throughout the world, particularly in Asia and the Middle East. The research described here promises to deliver economies to the Australian construction industry as well as equipping local firms involved in structural design to better compete for offshore work .
Community benefits will take the form of reduced construction costs and the capacity for a more complete and up to date knowledge of the structural performance and risk of aging assets, thereby increasing community confidence and safety.Read moreRead less
Borderline Personality as Social Phenomena. Mental disorders attract social stigma and those diagnosed are widely misunderstood. This project aims to collect and analyse accounts of people living with Borderline Personality Disorder (BPD) - mainly women - and perspectives of social support practitioners. The intended outcome is to provide a sophisticated understanding of BPD as a social phenomenon, develop sociological evidence based on lived experiences and generate Australian digital resources ....Borderline Personality as Social Phenomena. Mental disorders attract social stigma and those diagnosed are widely misunderstood. This project aims to collect and analyse accounts of people living with Borderline Personality Disorder (BPD) - mainly women - and perspectives of social support practitioners. The intended outcome is to provide a sophisticated understanding of BPD as a social phenomenon, develop sociological evidence based on lived experiences and generate Australian digital resources including narratives of BPD, creative outputs and practitioner perspectives. The anticipated goal of this project is to inform policy and community responses addressing stigma and marginalisation, and the improvement of social support for those affected by BPD.Read moreRead less
Predicting the diagnostic performance of individuals and organisations. Predicting the diagnostic performance of individuals and organisations. This project aims to address diagnostic error in advanced technology systems, by providing a mechanism to assess and improve individual diagnosticians’ performance. Organisations that rely on their employees’ diagnostic skills rarely assess them once the operators become qualified, so there is no basis for interventions that might prevent diagnostic erro ....Predicting the diagnostic performance of individuals and organisations. Predicting the diagnostic performance of individuals and organisations. This project aims to address diagnostic error in advanced technology systems, by providing a mechanism to assess and improve individual diagnosticians’ performance. Organisations that rely on their employees’ diagnostic skills rarely assess them once the operators become qualified, so there is no basis for interventions that might prevent diagnostic errors affecting thousands. This research tests a new method of assessing diagnostic skills based on how skilled operators respond to cues. This project will test how employees’ diagnostic skills change and whether this change corresponds to measures of organisational performance. This research is expected to provide organisations with a tool to pre-empt diagnostic errors that could minimise costs to the economy.Read moreRead less
Geomagnetic induced currents in the Australian electricity supply network. This project will develop measures to protect the Australian electricity supply network from adverse effects of enhanced solar activity. This is essential for risk assessment and long term asset management of the Australian electricity network.
Information Seeking & Research Adoption: Assessing Communication Strategies. This project aims to determine the best ways to communicate wine research and to design tools to support research adoption. Adoption of research relies on effective use of information and technology by employees. Research into employees’ information practices in the workplace has been conducted in health care, education and other areas; however, the wine industry’s use of information and technology for adoption is unexp ....Information Seeking & Research Adoption: Assessing Communication Strategies. This project aims to determine the best ways to communicate wine research and to design tools to support research adoption. Adoption of research relies on effective use of information and technology by employees. Research into employees’ information practices in the workplace has been conducted in health care, education and other areas; however, the wine industry’s use of information and technology for adoption is unexplored. The project plans to assess the strategies used to share research with winemakers and grape growers (e.g. seminars, websites, social media), from information behaviour or web useability perspectives, to ensure industry needs are met appropriately. This research aims to have a direct and immediate impact on the wine industry. In addition to the immediate impact of new research innovations that will be implemented by our partner wine companies, the project will also change industry-wide approaches to extension. The partner organisations use extension strategies to showcase new innovations and our research will assess these organisations’ current practices, providing evidence to shape the design of future activities in Australia.Read moreRead less
DEEP DRILLING OF THE HUMAN PLASMA PROTEOME. Like turning out city lights lets you see the faint stars more clearly - removal of high abundance proteins from human biofluids allows quantum leaps in biomarker discovery. This project will develop products that remove the biggest obstacle in proteomics - high abundance proteins (city lights). Cheap, efficient and routine removal of abundant proteins will amplify the power of ?cutting edge? proteomic technologies in the discovery of novel biomarkers ....DEEP DRILLING OF THE HUMAN PLASMA PROTEOME. Like turning out city lights lets you see the faint stars more clearly - removal of high abundance proteins from human biofluids allows quantum leaps in biomarker discovery. This project will develop products that remove the biggest obstacle in proteomics - high abundance proteins (city lights). Cheap, efficient and routine removal of abundant proteins will amplify the power of ?cutting edge? proteomic technologies in the discovery of novel biomarkers. This is possible because undiscovered low copy number biomarkers (faint stars) exist in human diagnostic fluids at levels far lower than current proteomic array detection limits.Read moreRead less
Re-conceptualising services from the perspectives of young people. This project aims to contribute the perspectives and voices of vulnerable young people to debates on the need for service reform. It will actively engage children and teens who have complex support needs in service re-design and decision making, and will trial child-led service initiatives. It will also explore organisational barriers to including young people in policy debate and service decision-making. Expected outcomes includ ....Re-conceptualising services from the perspectives of young people. This project aims to contribute the perspectives and voices of vulnerable young people to debates on the need for service reform. It will actively engage children and teens who have complex support needs in service re-design and decision making, and will trial child-led service initiatives. It will also explore organisational barriers to including young people in policy debate and service decision-making. Expected outcomes include increased knowledge of how to effectively engage young people, and understanding of the impact of their participation both for young people and for services. Read moreRead less