Development of a Prothrombogenic Bone Graft Substitute. The clinical demand for bone is massive and to counter this bone can be either harvested from the patient or bone substitutes are used. The success or failure of a bone substitute is determined the instant it come into contact with blood. The surfaces of traditional biomaterials induce a foreign body reaction. The aim of this project is to test the bone forming capacity of a biomaterial that is optimised to produce a natural response from ....Development of a Prothrombogenic Bone Graft Substitute. The clinical demand for bone is massive and to counter this bone can be either harvested from the patient or bone substitutes are used. The success or failure of a bone substitute is determined the instant it come into contact with blood. The surfaces of traditional biomaterials induce a foreign body reaction. The aim of this project is to test the bone forming capacity of a biomaterial that is optimised to produce a natural response from the blood. This response will lead to the formation new viable tissue and eventually bone. Such a material will cause faster bone healing, less pain from graft sites, shorter hospital stays and shorter waiting lists. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100115
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploi ....High-temperature probes for investigating phase transitions and reaction kinetics in thin films, nanostructured materials and biomaterials. This infrastructure for high temperature surface analysis and in-situ diagnostics as a function of temperature and gas environments will enhance Australia's capabilities in creating new materials for devices that will meet needs in medical, communications, environmental and security applications. The facility will enable researchers to understand and exploit interfacial phenomena and to tailor processing-microstructure-composition correlations, so as to design new materials with the best performance possible. Probes with unique capabilities will measure surface morphology, optical properties, elemental composition and crystallographic phase.The facility will be the first in Australia to offer a comprehensive study of structure and properties at high temperature.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668506
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
A Multi-Axis Biomaterials Testing Facility. Damage to bones and joints, due to injury or diseases such as osteoporosis and arthritis, is a major cause of disability and cost to the nation. Australia's ageing population contributes not only to an increasing incidence of such conditions, but also to more patients out-living implants such as replacement joints. In 2001-2, Australia spent over $800 million on joint replacement. Because over 11% of procedures are revisions of failed implants, even sm ....A Multi-Axis Biomaterials Testing Facility. Damage to bones and joints, due to injury or diseases such as osteoporosis and arthritis, is a major cause of disability and cost to the nation. Australia's ageing population contributes not only to an increasing incidence of such conditions, but also to more patients out-living implants such as replacement joints. In 2001-2, Australia spent over $800 million on joint replacement. Because over 11% of procedures are revisions of failed implants, even small improvements in implant life represent significant cost savings. By accurately simulating conditions within the body, this biomechanical testing facility will lead to new developments in implant designs and materials, in turn improving quality of life, productivity and treatment costs.Read moreRead less