Ecology, morphology and the diversification of Australian lizards. This project aims to determine the factors driving the spectacular radiation of lizards in Australia. To date, most investigations of lizard anatomy have focused exclusively on external characteristics. This project will examine the underlying internal anatomy to investigate whether morphological innovation is associated with enhanced rates of ecological, life-history and species diversification. The project expects to shed light ....Ecology, morphology and the diversification of Australian lizards. This project aims to determine the factors driving the spectacular radiation of lizards in Australia. To date, most investigations of lizard anatomy have focused exclusively on external characteristics. This project will examine the underlying internal anatomy to investigate whether morphological innovation is associated with enhanced rates of ecological, life-history and species diversification. The project expects to shed light on the evolution of Australia’s most diverse vertebrate lineage, and provide comparative data with which to interpret the lizard fossil record in Australia, and the range declines and relative extinction risks of native lizard species.Read moreRead less
Testing metabolic theories in ecology. There are striking similarities in the way plants and animals take up and use energy (metabolism), despite enormous variation in size and life-style. This project will make the first experimental comparison of the predictions of the two major theories for these broad patterns. The results will significantly progress this controversial and exciting field.
Building giants: the origins of extreme biology in baleen whales. Baleen whales are unlike any other animal. They have evolved unparalleled specialisations for feeding, hearing, smell, cognition and – above all – the largest ever body size. These extreme features underlie the unmatched dominance of baleen whales in today's oceans. The origins of these key adaptations required major changes in the anatomy and function of the skull and teeth. However, exactly how and when the extreme innovations o ....Building giants: the origins of extreme biology in baleen whales. Baleen whales are unlike any other animal. They have evolved unparalleled specialisations for feeding, hearing, smell, cognition and – above all – the largest ever body size. These extreme features underlie the unmatched dominance of baleen whales in today's oceans. The origins of these key adaptations required major changes in the anatomy and function of the skull and teeth. However, exactly how and when the extreme innovations of baleen whales began remains an outstanding question in animal biology. This proposal aims to combine exceptional Australian fossils with recent advances in 3D imaging, biomechanics, and evolutionary analysis to discover how the secrets to the success of baleen whales first evolved.Read moreRead less
Islands of rocks: geckos as a model system to understand patterns of biodiversity, endemism and speciation in the Kimberley. Australia is renowned for its diversity of lizards, yet a plethora of new "cryptic" gecko species continue to be discovered. The project will densely sample the complex Kimberley to understand the evolution of its geckos, which will shed light on true levels of species diversity and the geological and environmental history of this biodiversity hotspot.
ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the ....ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the whole genome as large inserts in BAC vectors, and build a "golden path" with minimal overlap. We will construct libraries of expressed genes from tammar tissues and array them for use in analysing gene expression.Read moreRead less
Development of molecular markers for resistance to blackleg disease (Leptosphaeria maculans) in canola. Canola (Brassica napus) is a valuable oil seed crop grown in many parts of the world and contributes annually $A450 million to the Australian economy. The overall aim of this project is to develop molecular markers for blackleg resistance using Australian germplasm along with evaluation in Australian disease nurseries which are regarded worlwide to develop the highest levels of disease pressu ....Development of molecular markers for resistance to blackleg disease (Leptosphaeria maculans) in canola. Canola (Brassica napus) is a valuable oil seed crop grown in many parts of the world and contributes annually $A450 million to the Australian economy. The overall aim of this project is to develop molecular markers for blackleg resistance using Australian germplasm along with evaluation in Australian disease nurseries which are regarded worlwide to develop the highest levels of disease pressure. Once molecular marker systems are developed and evaluated, they will be applied to facilitate the selection of Nugrain's (Industry Partner) canola breeding programs. Any molecular markers and QTL developed for Australian cultivars would find commercial application in breeding programmes.Read moreRead less
Chromatin barriers in Plasmodium falciparum gene regulation. Malaria is a major world disease that kills around 2 million people annually. The genome of the causative agent has now been completely sequenced, but we still know very little of how and why some genes are activated while their neighbours are turned off. I will study the DNA barriers that separate such genes, and the proteins that interact with these regions to better understand how genetic regulation functions in these parasites. A b ....Chromatin barriers in Plasmodium falciparum gene regulation. Malaria is a major world disease that kills around 2 million people annually. The genome of the causative agent has now been completely sequenced, but we still know very little of how and why some genes are activated while their neighbours are turned off. I will study the DNA barriers that separate such genes, and the proteins that interact with these regions to better understand how genetic regulation functions in these parasites. A better understanding of gene regulation in malaria parasites will help us to better combat the tricks utilised by this and other organisms to elude our immune systems.Read moreRead less
Social Glue? The contribution of sport and active recreation to community wellbeing. Australian federal, state and local governments allocate more than $4,094 million per year to the provision of sport and recreation services, facilities and programs which service more than 5 million regular participants. This funding is, in part, based on the premise that involvement in sport and recreation develops community wellbeing through the facilitation of social inclusion and connectedness. This researc ....Social Glue? The contribution of sport and active recreation to community wellbeing. Australian federal, state and local governments allocate more than $4,094 million per year to the provision of sport and recreation services, facilities and programs which service more than 5 million regular participants. This funding is, in part, based on the premise that involvement in sport and recreation develops community wellbeing through the facilitation of social inclusion and connectedness. This research will contribute to the development of policies and practices that will enhance the capability of sport and active recreation organisations to contribute to community wellbeing.Read moreRead less
Statistical methods for detection of non-coding RNAs in eukaryote genomes. Understanding how eukaryotic cells work is a major goal of 21st century biology. A crucial step will be to catalogue the functional components of eukaryotic genomes. Australian researchers must be involved in this process at an early stage, in order to maximise commercial opportunities, attract quality researchers and position ourselves for further advances. This project will make major contributions to international effo ....Statistical methods for detection of non-coding RNAs in eukaryote genomes. Understanding how eukaryotic cells work is a major goal of 21st century biology. A crucial step will be to catalogue the functional components of eukaryotic genomes. Australian researchers must be involved in this process at an early stage, in order to maximise commercial opportunities, attract quality researchers and position ourselves for further advances. This project will make major contributions to international efforts in this area, via the development of statistical methods for segmenting genomes, classification of those segments, and study of the resulting classes. In the long term, enhanced understanding of eukaryotic cells will lead to breakthroughs in biology, and to medical, pharmaceutical, agricultural and scientific advances.Read moreRead less
Enhancing wellbeing over the family life course. This project aims to investigate the impact of family life transitions, such as relationship formation and dissolution or births, on wellbeing over the life course. It will do this by analysing data following people over time and will provide information about the negative and positive effects of family transitions for wellbeing, track changes in wellbeing before, during and after transitions, and highlight the intersections of the family life cou ....Enhancing wellbeing over the family life course. This project aims to investigate the impact of family life transitions, such as relationship formation and dissolution or births, on wellbeing over the life course. It will do this by analysing data following people over time and will provide information about the negative and positive effects of family transitions for wellbeing, track changes in wellbeing before, during and after transitions, and highlight the intersections of the family life course with gender, age and socioeconomic status. This will considerably enhance understandings of wellbeing over the family life course, providing insights for targeted policies and interventions to improve health and wellbeing.Read moreRead less