LATERAL GENE TRANSFER, GENOME EVOLUTION AND THE EMERGENCE OF NEW DISEASES CAUSED BY FUNGAL PATHOGENS IN THE PLEOSPORALES. Normal evolution involves the transfer of genes within species. The modest variation between progeny powers natural selection. Lateral gene transfer is the movement of genetic material between species. It allows for large evolutionary steps. Although common in bacteria, it has rarely been described convincingly in higher organisms such as fungi, plants or animals. We have evi ....LATERAL GENE TRANSFER, GENOME EVOLUTION AND THE EMERGENCE OF NEW DISEASES CAUSED BY FUNGAL PATHOGENS IN THE PLEOSPORALES. Normal evolution involves the transfer of genes within species. The modest variation between progeny powers natural selection. Lateral gene transfer is the movement of genetic material between species. It allows for large evolutionary steps. Although common in bacteria, it has rarely been described convincingly in higher organisms such as fungi, plants or animals. We have evidence that one group of fungal pathogens is particularly adept at acquiring new genes that enable them to cause new diseases. We will determine the mechanism and frequency of gene transfer in this group. The work had fundamental significance in evolutionary biology, in the emergence of new diseases and in the use of genetically-modified organisms.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560987
Funder
Australian Research Council
Funding Amount
$156,697.00
Summary
Robust High Resolution Gene and Protein Expression Analysis Facilities in WA. Biological research is playing an increasingly important role in keeping agriculture internationally competitive and helping to unravel the basic mechanisms underpinning plant and animal health. This collaborative research equipment will greatly enhance and extend our existing functional genomic facilities in WA, allowing robust pre-fractionation of samples for directed proteomic analysis within complex systems and al ....Robust High Resolution Gene and Protein Expression Analysis Facilities in WA. Biological research is playing an increasingly important role in keeping agriculture internationally competitive and helping to unravel the basic mechanisms underpinning plant and animal health. This collaborative research equipment will greatly enhance and extend our existing functional genomic facilities in WA, allowing robust pre-fractionation of samples for directed proteomic analysis within complex systems and allowing accurate and sensitive measurement of gene expression. Both of these are critical for analysis of low abundance components involved in signalling and regulatory functions in biological samples.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453722
Funder
Australian Research Council
Funding Amount
$385,240.00
Summary
Collaborative Genomics, Proteomics and Metabolomics Facility for Western Australia. Plant and animal agriculture in Western Australia contributes $6billion per annum to the nation. Biotechnology is playing an increasingly important role in keeping agriculture internationally competitive, and requires investment in platform technologies to underpin basic and applied research. This collaborative project will provide state-of-the-art equipment and extend existing joint facilities that will enable ....Collaborative Genomics, Proteomics and Metabolomics Facility for Western Australia. Plant and animal agriculture in Western Australia contributes $6billion per annum to the nation. Biotechnology is playing an increasingly important role in keeping agriculture internationally competitive, and requires investment in platform technologies to underpin basic and applied research. This collaborative project will provide state-of-the-art equipment and extend existing joint facilities that will enable WA researchers to carry out high quality research on genomics, proteomics and the metabolic functioning of plants and animals. This will generate new knowledge, provide advanced training and help ensure that Australian R&D in agricultural biotechnology stays at the forefront and benefits the nation.Read moreRead less
Genomic Synteny in Legumes; Application to Crop Breeding. Synteny is defined as the degree of colinearity between the order of orthologous genes in chromosomes of related species. New data suggests that legumes share widespread synteny. Extensive genomic resources are being accumulated for the model legume, Medicago truncatula including the full genome sequence. We propose to use these resources to uncover patterns of synteny between M. truncatula and the cultivated legumes chickpeas, lupins, ....Genomic Synteny in Legumes; Application to Crop Breeding. Synteny is defined as the degree of colinearity between the order of orthologous genes in chromosomes of related species. New data suggests that legumes share widespread synteny. Extensive genomic resources are being accumulated for the model legume, Medicago truncatula including the full genome sequence. We propose to use these resources to uncover patterns of synteny between M. truncatula and the cultivated legumes chickpeas, lupins, faba-beans, lentils and lucerne. In addition to revealing patterns of chromosomal evolution in this large plant family, we will generate genetic maps and molecular markers for use in practical plant breeding of these important crops.Read moreRead less