Modelling and Performance Evaluation of Stab and Ballistic Resistant Fabrics. The aims of the project are to model and design stab resistant fabrics, and evaluate their stab and ballistic performance under simulated end-use conditions. Bi-component ballistic and stab resistant wearable and concealable garments will be produced and comprehensively characterised. This program is a significant first step towards developing Australian owned intellectual property for specialised protective garments f ....Modelling and Performance Evaluation of Stab and Ballistic Resistant Fabrics. The aims of the project are to model and design stab resistant fabrics, and evaluate their stab and ballistic performance under simulated end-use conditions. Bi-component ballistic and stab resistant wearable and concealable garments will be produced and comprehensively characterised. This program is a significant first step towards developing Australian owned intellectual property for specialised protective garments for local and export markets. Results from this study will produce fundamental knowledge on stab and ballistic resistant fabrics and armours, and provide practical information on the preparation of commercially acceptable protective products.Read moreRead less
Multilayered Safety Clothing for Personal Protective Equipment. This project aims to improve multilayered firefighting protective garments and their thermal comfort by utilizing aerogel microparticles containing thermal regulation materials and flame-retardant agents. This research will create new multifunctional fabric designs and engineering techniques to integrate improved heat and flame protection, comfort and smart features into optimized multilayered garments. It will create novel clothing ....Multilayered Safety Clothing for Personal Protective Equipment. This project aims to improve multilayered firefighting protective garments and their thermal comfort by utilizing aerogel microparticles containing thermal regulation materials and flame-retardant agents. This research will create new multifunctional fabric designs and engineering techniques to integrate improved heat and flame protection, comfort and smart features into optimized multilayered garments. It will create novel clothing systems that will better protect wearers and allow them to effectively combat bushfires and save lives and assets. The successful completion will enable industrial capability in next generation advanced protective garments and functional uniforms for broad occupational health safety and well-being applications.Read moreRead less
Advanced three-dimensional fibrous structures for vascular graft applications. This project will combine advanced three-dimensional fabric structures, surface functionalisation and haemodynamic modelling to tackle critical issues in the design and manufacture of vascular graft materials. It will lead to the next generation of vascular grafts with much enhanced structural and biomedical performance.
Microstructure effect on energy harvesting ability of electrospun fibres. This project aims to provide new knowledge about how to manipulate the energy harvesting ability of electrospun fibrous mats by changing the fibre structure, components and mat configuration. Expected outcomes of the project are new fibrous materials capable of efficiently converting small mechanical forces and sounds into electricity. These high performance energy harvesting fibres will be useful for developing new power ....Microstructure effect on energy harvesting ability of electrospun fibres. This project aims to provide new knowledge about how to manipulate the energy harvesting ability of electrospun fibrous mats by changing the fibre structure, components and mat configuration. Expected outcomes of the project are new fibrous materials capable of efficiently converting small mechanical forces and sounds into electricity. These high performance energy harvesting fibres will be useful for developing new power supplies, self-powered electronics, self-sustainable sensor networks and electronic textiles.Read moreRead less
Fibre-sized energy generators and storage in multi-functional fabrics. This project proposes to do away with conventional batteries for powering portable or wearable devices by developing wearable fabrics capable of energy generation. The outcome will be a robust fabric with the capability of powering wearable or portable devices in the communications, health-care, sports and defence industries.
High Temperature, Piezoelectric Polymer Membranes. This project aims to acquire new knowledge about the preparation of flexible polymer membranes that can convert mechanical energy into electricity (“piezoelectric” conversion) stably at high temperature (e.g. 200-500 °C). This will solve the current problem where only inorganic ceramic materials can be used for high-temperature piezoelectric conversion. The expected outcomes include a new approach to prepare polymer membranes capable of high-tem ....High Temperature, Piezoelectric Polymer Membranes. This project aims to acquire new knowledge about the preparation of flexible polymer membranes that can convert mechanical energy into electricity (“piezoelectric” conversion) stably at high temperature (e.g. 200-500 °C). This will solve the current problem where only inorganic ceramic materials can be used for high-temperature piezoelectric conversion. The expected outcomes include a new approach to prepare polymer membranes capable of high-temperature piezoelectric conversion using an electrostatic spinning technology. The new breakthrough materials will not only enhance performance and reliability at high temperature, but also offer novel applications in diverse fields such as “smart” protective clothing for firefighters. Read moreRead less
Self-powered active noise control via a nanofibre acoustoelectric converter. This project aims to investigate a new, active noise control system that can eliminate low frequency noise without the use of external electricity. This project will generate new knowledge about how to realise self-powering on active noise controllers using piezoelectric nanofibres as sound detector and power generator. Expected outcomes include an effective method to produce this novel noise controller and a systemic u ....Self-powered active noise control via a nanofibre acoustoelectric converter. This project aims to investigate a new, active noise control system that can eliminate low frequency noise without the use of external electricity. This project will generate new knowledge about how to realise self-powering on active noise controllers using piezoelectric nanofibres as sound detector and power generator. Expected outcomes include an effective method to produce this novel noise controller and a systemic understanding about materials, devices and performance. This will significantly benefit development of advanced noise controlling technology and products, benefiting industry and the environment.Read moreRead less
Investigating Wnt signaling during human nephron commitment and patterning. Aims: To use gene edited stem cell lines that display cell location, identity and cell state to map human kidney tissue formation in the laboratory. By monitoring how each cell responds to those around it across time and space, we will for the first time map the formation of kidney tissue in the dish.
Significance: Understanding how stem cells form a tissue will help us to improve and control the process. This is key to ....Investigating Wnt signaling during human nephron commitment and patterning. Aims: To use gene edited stem cell lines that display cell location, identity and cell state to map human kidney tissue formation in the laboratory. By monitoring how each cell responds to those around it across time and space, we will for the first time map the formation of kidney tissue in the dish.
Significance: Understanding how stem cells form a tissue will help us to improve and control the process. This is key to advancing tissue engineering.
Expected outcomes: The proposal will pioneer state-of-the-art imaging, gene editing and machine learning approaches, generating models of human development that are currently unavailable.
Benefits: This understanding will guide the development of novel approaches to tissue engineering.
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Investigating the dynamic nature of antibody stability. The aim of the project is to provide insights into the molecular mechanisms of antibody stability. Monoclonal antibodies have transformed the study of biological processes and represent blockbuster therapeutics for cancer and inflammation. Unfortunately, antibodies often display limited stability, which greatly hinders development. Mutations have recently been identified that render human antibodies resistant to aggregation, and high-resolu ....Investigating the dynamic nature of antibody stability. The aim of the project is to provide insights into the molecular mechanisms of antibody stability. Monoclonal antibodies have transformed the study of biological processes and represent blockbuster therapeutics for cancer and inflammation. Unfortunately, antibodies often display limited stability, which greatly hinders development. Mutations have recently been identified that render human antibodies resistant to aggregation, and high-resolution crystal structures are being used to identify function. Intriguingly, preliminary data indicates that the mutations do not affect the native antibody structure, but rather influence dynamic states. The project plans to use a combination of mutagenesis, molecular dynamics simulation and deuterium exchange to study antibody dynamics.Read moreRead less
The true potential and limitations of fibres. This project aims to understand the fibre spinning process of nanomaterials to identify their true potential and limitations in wearable applications. The project is expected to lead to multifunctional materials that allow design and production of smart functional fibres and textiles that store and convert energy and sense, monitor and respond to human activities and external environments. The project outcomes are expected to accelerate the transform ....The true potential and limitations of fibres. This project aims to understand the fibre spinning process of nanomaterials to identify their true potential and limitations in wearable applications. The project is expected to lead to multifunctional materials that allow design and production of smart functional fibres and textiles that store and convert energy and sense, monitor and respond to human activities and external environments. The project outcomes are expected to accelerate the transformation of the fibre industry, which will have far reaching implications across research disciplines and sectors critical to technology, health, social, and economic future.Read moreRead less