The molecular role of ADAM12 in maintenance of skeletal muscle, myogenesis and adipogenesis. An understanding of the molecular control of skeletal muscle growth, maintenance and balance between muscle and fat production is of fundamental importance for a competitive meat industry, for the promotion of strong muscles in the ageing population and for disorders such as muscle diseases, diabetes and obesity. This project will enhance strong international collaborations and expand cutting-edge resear ....The molecular role of ADAM12 in maintenance of skeletal muscle, myogenesis and adipogenesis. An understanding of the molecular control of skeletal muscle growth, maintenance and balance between muscle and fat production is of fundamental importance for a competitive meat industry, for the promotion of strong muscles in the ageing population and for disorders such as muscle diseases, diabetes and obesity. This project will enhance strong international collaborations and expand cutting-edge research within Australia with many potential economic benefits for the meat industry, biotechnology and health. The expertise developed by this pioneering research will ensure that Australia is well placed to harness new technologies and exploit future advances in this fast-moving field of muscle biology.Read moreRead less
Special Research Initiatives - Grant ID: SR0354622
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the early embryo have major consequences for the development of individuals. The aim of this Network is to harness the resources of leading researchers from the previously distinct disciplines of developmental biology and developmental physiology to better understand developmental regulatory networks and how environmental factors impinge on them. The formation of such a Network ....Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the early embryo have major consequences for the development of individuals. The aim of this Network is to harness the resources of leading researchers from the previously distinct disciplines of developmental biology and developmental physiology to better understand developmental regulatory networks and how environmental factors impinge on them. The formation of such a Network is unique, timely and strategic in that it will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory ne ....ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory networks and to address how environmental factors impinge on these regulatory networks. The formation of this National Research Network is unique, timely and strategic. It will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
Sex, Sperm and Society. Insights into the evolutionary potential of sexual conflict in insects: a fundamental question in evolutionary biology. Social insects are biologically and economically important species. Honeybees or stingless bees are used for crop pollination and honey production and invasive ants or termites are severe pest species causing economic damage. Part of the biological success of social insects is based on the capability to produce colonies with many workers although colonie ....Sex, Sperm and Society. Insights into the evolutionary potential of sexual conflict in insects: a fundamental question in evolutionary biology. Social insects are biologically and economically important species. Honeybees or stingless bees are used for crop pollination and honey production and invasive ants or termites are severe pest species causing economic damage. Part of the biological success of social insects is based on the capability to produce colonies with many workers although colonies typically contain only one or very few reproductives. Consequently, colony success is bound to queen fertility and studying social insect reproduction can therefore optimize breeding regimes of species of interest or offer new possibilities to control pest species. Detailed information on sperm form and function will provide pioneering insights into the complexity of sexual reproduction.Read moreRead less
Better bees for tomorrow: A proteomic and physiological characterization of male fertility in managed versus feral honeybees in Western Australia. The importance of honeybees for food production is often undervalued as they pollinate more than 80 crops of economic interest. However, honeybee populations are on a worldwide decline and the beekeepers struggle to survive economically. Australia has so far been spared of major collapses but this seems merely a question of time. The work proposed ini ....Better bees for tomorrow: A proteomic and physiological characterization of male fertility in managed versus feral honeybees in Western Australia. The importance of honeybees for food production is often undervalued as they pollinate more than 80 crops of economic interest. However, honeybee populations are on a worldwide decline and the beekeepers struggle to survive economically. Australia has so far been spared of major collapses but this seems merely a question of time. The work proposed initiates a close collaboration between the only honeybee-breeding organization in Western Australia and the University of Western Australia. Scientific research to ensure a future supply of managed and healthy honeybees is initiated to understand honeybee reproduction, diseases and immunity in more detail. The results are expected to be of interest for the entire Australian honeybee industry.Read moreRead less