Understanding The Mechanisms Of Substrate And Ubiquitin Lysine Specificity During Ubiquitination
Funder
National Health and Medical Research Council
Funding Amount
$573,993.00
Summary
Ubiquitin is a small molecule which controls all facets of a cell's growth and biology, such as growth. Ubiquitin functions by being attached to proteins in cells to alter their function and hence a particular chemical pathway. How ubiquitin is attached to proteins is poorly understood. This studiy will unveil how enzymes termed Ubcs attach ubiquitin to proteins, which is fundamental to understanding how ubiquitn controls cell functions.