The Burden Of Cancer - Prevention, Treatments, Costs, And Related Diseases
Funder
National Health and Medical Research Council
Funding Amount
$311,860.00
Summary
This research aims to increase knowledge on the development, optimal treatment, and costs of cancer and the associated risk factors, by applying advanced disease burden measures to comprehensive data gathered from several established and novel databases. This knowledge is important in advancing our understanding of those most vulnerable to cancer and in developing appropriate preventive strategies and health care for those at highest risk.
Using An Established Simulation Model To Determine Effective And Cost-effective Interventions To Mitigate Influenza Pandemics And Inform Public Health Policy
Funder
National Health and Medical Research Council
Funding Amount
$416,353.00
Summary
A novel disease spread and economic model is used to determine the cost-effectiveness of a range of mitigation strategies aimed at a future influenza pandemic. A simulation model generates data on which individuals become ill, morbidity and mortality characteristics, an economic costing model determines optimal interventions.
Osteoporotic Fracture-Mortality Association And The Effect Of Anti-osteoporosis Treatment: A Multinational Study
Funder
National Health and Medical Research Council
Funding Amount
$84,800.00
Summary
Osteoporosis burden is due primarily to osteoporotic fractures resulting in economic and public health burden, increased disability, further fracture risk and more importantly early death. However, it remains under-treated although treatment reduces the number of fractures and may reduce early death. This study aims to understand which types of fractures result in early death and for which age groups and whether osteoporosis treatment does or does not reduce early death.
Long-term Outcome After Stroke: Survival, Stroke Recurrence, Functional Ability And Costs.
Funder
National Health and Medical Research Council
Funding Amount
$649,971.00
Summary
Stroke is the third most common cause of death in Australia, and is more common in the older age groups. Because the population most at risk of developing stroke is growing faster than the rest of the population, it is likely that there will be a large increase in the number of strokes occurring in coming years. At 1 year after stroke about one-third of patients have died, a third remain severely disabled and a third recover with minimal disability. In Australia, there is no information on outco ....Stroke is the third most common cause of death in Australia, and is more common in the older age groups. Because the population most at risk of developing stroke is growing faster than the rest of the population, it is likely that there will be a large increase in the number of strokes occurring in coming years. At 1 year after stroke about one-third of patients have died, a third remain severely disabled and a third recover with minimal disability. In Australia, there is no information on outcome beyond 5 years. It is thought that at 10 years after stroke about 70% of patients will have died, and a further 5-10% will have had another nonfatal stroke. The aim of this study is to assess the long-term outcome of patients with stroke. These will include measures of survival, stroke recurrence, and ability to perform usual daily activities. The use of health care and community resources and the associated costs of this will also be assessed. Information on survival patterns, stroke recurrence, disability and costs will be of great value for health service planning. Such information will also be useful to patients, their families, and medical staff who treat these patients.Read moreRead less
Evaluation Of Long-Term Clinical And Health Service Outcomes Following Coronary Artery Revascularisation In Western Australia: Future Implications
Funder
National Health and Medical Research Council
Funding Amount
$638,412.00
Summary
Heart attacks occur when arteries of the heart become blocked, and current treatment involves unblocking the affected vessel by inserting a stent fed through a leg artery or using bypass surgery. There are different types of stents and whether they offer better outcomes than surgery in the long-term is currently undecided. We will evaluate whether patients who receive stents have better outcomes after 5 years than patients who have surgery, and what the various costs are to the health system.
Prevention Of Multi-drug Resistant Tuberculosis In A High Prevalence Setting: ‘Connecting The DOTS’ In Vietnam
Funder
National Health and Medical Research Council
Funding Amount
$3,382,020.00
Summary
The close contacts of people with multi-drug resistant tuberculosis (MDR-TB) have a high risk of developing the disease. The V-QUIN MDR-TB Trial will evaluate the effectiveness of an oral antibiotic (levofloxacin) in preventing drug resistant TB among infected household contacts of TB patients. Household contacts from 10 Provinces in Vietnam will be randomly allocated to receive six-months of either levofloxacin or a placebo, and then followed for two years to see if they develop tuberculosis.
Testing And Treatment For Prostate Cancer In Australia: Epidemiology And Modelling
Funder
National Health and Medical Research Council
Funding Amount
$267,886.00
Summary
We aim to use observational data and mathematical modelling to investigate testing and treatment for prostate cancer in Australia. We will incorporate changes in prostate-specific antigen (PSA) testing and in clinical practice to investigate: a) over-diagnosis, being cancer cases diagnosed through PSA testing that would not have been otherwise diagnosed; b) the effect of PSA testing on prostate cancer mortality; and c) mortality and health care use under different PSA test scenarios.