Ketamine Therapy Among Patients With Treatment-resistant Depression: A Randomised, Double-blind, Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,069,382.00
Summary
In the last decade, there have been reports of powerful antidepressant effects after a single injection of anaesthetic ketamine, with dramatic (though shortlasting) effects within 24 hours. This will be the first controlled study to test whether a course of repeated ketamine treatments, given over 4 weeks, is effective and safe in treating depression.
Ageing in prison: A strategic framework for the management of ageing offenders in the Australian criminal justice system. The knowledge and strategies offered by this research will contribute to significant improvements in planning of programs and facilities for Australian prisons and prisoner support services. In turn, ageing prisoners will benefit from improved mental and physical health, reduction in homelessness, and reduced recidivism. Improved knowledge of the needs of ageing prisoners wil ....Ageing in prison: A strategic framework for the management of ageing offenders in the Australian criminal justice system. The knowledge and strategies offered by this research will contribute to significant improvements in planning of programs and facilities for Australian prisons and prisoner support services. In turn, ageing prisoners will benefit from improved mental and physical health, reduction in homelessness, and reduced recidivism. Improved knowledge of the needs of ageing prisoners will allow reduced costs, through better planning, less inefficiencies and a decreased burden on community health and welfare systems. The project will also assist government departments to ensure national and international human rights obligations are met.Read moreRead less
The impact of incarceration on children's care: a strategic framework for good care planning. This project will study best practice for care planning of children whose primary carers are incarcerated within the Australian criminal justice system. It will develop a strategic framework for future policy and practice in Australian care planning with the aim of improving outcomes for both parents and children.
Improving The Quality, Efficiency And Outcomes Of Stroke Care: Transforming Policy And Practice
Funder
National Health and Medical Research Council
Funding Amount
$466,492.00
Summary
This Fellowship supports an innovative body of research focussed on interventions to improve the care and outcomes of stroke. In Australia, stroke is a leading cause of death and disability. Unfortunately, variability in clinical care is resulting in some preventable disability. Over the next 4 years A/Prof Cadilhac will conduct clinical trials (n=2) and observational studies (n=3) aimed at improving the health system and outcomes of stroke. She uses economic evaluation to ensure findings are us ....This Fellowship supports an innovative body of research focussed on interventions to improve the care and outcomes of stroke. In Australia, stroke is a leading cause of death and disability. Unfortunately, variability in clinical care is resulting in some preventable disability. Over the next 4 years A/Prof Cadilhac will conduct clinical trials (n=2) and observational studies (n=3) aimed at improving the health system and outcomes of stroke. She uses economic evaluation to ensure findings are used for changing policy.Read moreRead less
Collaborative family work in youth justice: a model for reducing recidivism in young offenders. This project will research the effect of group family counselling on outcomes for juvenile offenders. It will draw conclusions about the factors related to successful family work and could significantly reduce re-offending in the juvenile justice population.
STROKE123: A Collaborative, National Effort To Monitor, Promote And Improve The Quality Of Stroke Care In Hospitals And Patient Outcomes.
Funder
National Health and Medical Research Council
Funding Amount
$1,261,292.00
Summary
Stroke is a major public health issue in Australia. This Better Health Initiative partnership project is designed to rigorously evaluate a methodology to improve the monitoring and use of data for stroke, as well as an intervention to address evidence-practice gaps for essential interventions known to have a direct association with patient outcomes. The findings will provide a platform for national roll-out of appropriate and enhanced data collection solutions linked to an effective model for im ....Stroke is a major public health issue in Australia. This Better Health Initiative partnership project is designed to rigorously evaluate a methodology to improve the monitoring and use of data for stroke, as well as an intervention to address evidence-practice gaps for essential interventions known to have a direct association with patient outcomes. The findings will provide a platform for national roll-out of appropriate and enhanced data collection solutions linked to an effective model for improving clinical care and outcomes of stroke.Read moreRead less
Testing A Tailored, Evidence-based Education Intervention To Enhance Outcomes For Patients Commencing Chemotherapy
Funder
National Health and Medical Research Council
Funding Amount
$311,250.00
Summary
This project tests an innovative education program aimed at reducing the physical and psychosocial burden experienced during a course of cancer chemotherapy. The aim of the study is to reduce the burden and distress associated with cancer chemotherapy. Cancer chemotherapy is associated with physical (nausea, fatigue, hair loss, infection) and psychosocial (fear, anxiety, worry about family) effects that cause significant distress. Patients experience a highly level of pre-treatment anxiety and f ....This project tests an innovative education program aimed at reducing the physical and psychosocial burden experienced during a course of cancer chemotherapy. The aim of the study is to reduce the burden and distress associated with cancer chemotherapy. Cancer chemotherapy is associated with physical (nausea, fatigue, hair loss, infection) and psychosocial (fear, anxiety, worry about family) effects that cause significant distress. Patients experience a highly level of pre-treatment anxiety and for many this distress lasts across the course of treatment. Over the past decade there has been a dramatic shift in chemotherapy delivery to the outpatient setting. This means that patients are now responsibile for monitoring their own health at home and may need to use self-care strategies to deal with the many adverse effects of treatment. Pre-treatment education has usually focused on providing information about the facts of treatment, i.e. likelihood of nausea, rather than preparing the patient for the experience of treatment or helping them to manage the self-care demands associated with receiving treatment in the outpatient setting. The innovative education program tested here is the first of its type to draw on high level research evidence about preparing patients for potentially threatening medical procedures, tailoring this education to the individual situation of the patient and coaching the patient to implement evidence-based self-care behaviours and to use stress reduction techniques across the course of treatment.Read moreRead less
The Evaluation of Stuctures and Processes for Effective Client, Carer and Community Outcomes: A Model for Rural Mental Health Services. The South West Healthcare Area Mental Health Service ( Warnambool) has demonstrated according to key performance indicators, an effective system of service delivery. This evaluative research project seeks to identify key components within the organisational structures and processes of a rural mental health service that contribute to these effective outcomes fo ....The Evaluation of Stuctures and Processes for Effective Client, Carer and Community Outcomes: A Model for Rural Mental Health Services. The South West Healthcare Area Mental Health Service ( Warnambool) has demonstrated according to key performance indicators, an effective system of service delivery. This evaluative research project seeks to identify key components within the organisational structures and processes of a rural mental health service that contribute to these effective outcomes for clients. The research process will test these key components against other rural and urban mental health services in Victoria and will result in the development of a model for rural mental health service delivery of both local and national significance.Read moreRead less
A Cluster RCT Of A Novel Psychological Intervention To Reduce Depression Among At-risk Older Adults Transitioning To Residential Aged Care
Funder
National Health and Medical Research Council
Funding Amount
$893,152.00
Summary
Depression is common in aged care facilities, with many older adults finding the transition extremely difficult. We have developed a simple intervention to help new residents, including those with dementia, to adjust to life in aged care. This program focuses on key aspects of psychological wellbeing, and is designed for widespread use in aged care. We will evaluate the intervention to determine if it is superior to current care approaches in reducing depression and improving quality of life.
This Centre of Research Excellence will translate the best available evidence to improve cancer outcomes through better management of infections in cancer patients, a rapidly growing group. We will establish new research networks to detect emerging multi resistant infections, develop guidelines on how to manage them, implement locally successful programs that have been shown to save lives nationally and validate new practice changing immune, bioinformatics and diagnostic technologies.