Mechanical modulation of particle-cell interactions. Mechanical forces play critical roles in many biological processes, but how particle mechanical properties modulate particle-cell interactions remains elusive. This project aims to develop new design principles for engineering nano/micromaterials with tunable mechanical properties for improved cell activation and expansion, and to advance knowledge of the role of particle stiffness in modulating receptor-mediated particle-cell interactions. Ex ....Mechanical modulation of particle-cell interactions. Mechanical forces play critical roles in many biological processes, but how particle mechanical properties modulate particle-cell interactions remains elusive. This project aims to develop new design principles for engineering nano/micromaterials with tunable mechanical properties for improved cell activation and expansion, and to advance knowledge of the role of particle stiffness in modulating receptor-mediated particle-cell interactions. Expected outcomes and benefits include new fundamental understanding of the effect of particle mechanical properties on cell function, new insights into T cell activation and expansion, and new classes of stiffness-tunable fit-for-purpose materials for various applications in cell manufacturing.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100032
Funder
Australian Research Council
Funding Amount
$4,272,072.00
Summary
ARC Training Centre in Fire Retardant Materials and Safety Technologies. The ARC Training Centre in Fire Retardant Materials and Safety Technologies aims to train a cohort of industry-focused researchers to improve the fire safety of lightweight materials and structures and fire protection systems. The Training Centre expects to create knowledge on novel green and durable fire retardant materials, advanced fire models for urban and built environment, fire suppression technologies, and new flamma ....ARC Training Centre in Fire Retardant Materials and Safety Technologies. The ARC Training Centre in Fire Retardant Materials and Safety Technologies aims to train a cohort of industry-focused researchers to improve the fire safety of lightweight materials and structures and fire protection systems. The Training Centre expects to create knowledge on novel green and durable fire retardant materials, advanced fire models for urban and built environment, fire suppression technologies, and new flammability tests for compliance with fire safety regulatory standards. An expected outcome of this Training Centre is to accelerate the transformation of Australia’s industries in fire retardant materials, products and engineering services.Read moreRead less
Tailoring nanocomposites with controllable structural-property relationship. This project aims to process and fabricate graphene-based materials into useful devices. Understanding nanocomposite structure-property relationships are crucial to rapidly develop functional devices. This project will use graphene in the form of nanocomposites and precisely construct them in devices via three-dimensional printing. This will be achieved through the polymer chemistry and interfacial engineering of graphe ....Tailoring nanocomposites with controllable structural-property relationship. This project aims to process and fabricate graphene-based materials into useful devices. Understanding nanocomposite structure-property relationships are crucial to rapidly develop functional devices. This project will use graphene in the form of nanocomposites and precisely construct them in devices via three-dimensional printing. This will be achieved through the polymer chemistry and interfacial engineering of graphene for enhanced dispersibility and self-assembly in the targeted polymer matrix, thus affording maximum synergistic properties. The project expects to develop three-dimensional printing techniques and control and understand the effect of micro-patterning and nano-structuring on printed graphene nanocomposites.Read moreRead less