ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the ....ARC Centre for Kangaroo Genome. In this Australian-led Kangaroo Genome Project, we will map and characterize the tammar wallaby genome at the molecular level. Marsupial genomes are uniquely valuable because they provide comparisons that reveal new human genes, regulatory sequences and marsupial-specific genes. These will deliver new products and information useful for medicine, industry, agriculture and conservation. We will construct integrated genetic and physical maps of the genome, clone the whole genome as large inserts in BAC vectors, and build a "golden path" with minimal overlap. We will construct libraries of expressed genes from tammar tissues and array them for use in analysing gene expression.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0667981
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Kangaroo Genome Resource Management Facility. Increasingly, large Australian multicentre research programs in biological and medical sciences have a genomics component that involves integration of biological information with sequencing data. The success of these research programs depends on rapid internet access to the research information by all participating scientists. The universal design of the proposed information management system means that it can be easily adapted to support a broad ran ....Kangaroo Genome Resource Management Facility. Increasingly, large Australian multicentre research programs in biological and medical sciences have a genomics component that involves integration of biological information with sequencing data. The success of these research programs depends on rapid internet access to the research information by all participating scientists. The universal design of the proposed information management system means that it can be easily adapted to support a broad range of research programs. The development of this software program therefore has the potential to benefit research scientists, academics and students in many related fields, as well as the broader community, through enhancing research outcomes.Read moreRead less
Rivers of Gold: The Legacy of Historical Gold Mining for Victoria's Rivers. By considering rivers as cultural artefacts, this project aims to evaluate how historical gold mining has shaped river systems in Victoria. Victoria’s historic mining industry led to extensive and long-lasting change to waterways across the state. The project plans to integrate approaches from landscape archaeology, physical geography, geomorphology and environmental chemistry to identify and map the extent of changes, i ....Rivers of Gold: The Legacy of Historical Gold Mining for Victoria's Rivers. By considering rivers as cultural artefacts, this project aims to evaluate how historical gold mining has shaped river systems in Victoria. Victoria’s historic mining industry led to extensive and long-lasting change to waterways across the state. The project plans to integrate approaches from landscape archaeology, physical geography, geomorphology and environmental chemistry to identify and map the extent of changes, including increased sedimentation, erosion, and chemical contamination. The project plans to demonstrate how historical mining continues to influence chemical and physical processes in Victorian streams and to develop understanding of the landscapes experienced by Victorians at the height of the mining boom. Project outcomes may provide improved context for catchment and reservoir management and counter prevailing impressions about causes of observed damage to rivers.Read moreRead less
Contemporary contestations over working time: should health weigh in? In the last 30 years, the demand for economic competitiveness has driven the growth in flexible employment conditions, with little consideration of the impacts on the nation’s health. Using mixed methods, the research tests a new theory that when governments deregulate labour markets they destabilise cultural practices, with potential health and well-being consequences. It also determines whether and how the health implication ....Contemporary contestations over working time: should health weigh in? In the last 30 years, the demand for economic competitiveness has driven the growth in flexible employment conditions, with little consideration of the impacts on the nation’s health. Using mixed methods, the research tests a new theory that when governments deregulate labour markets they destabilise cultural practices, with potential health and well-being consequences. It also determines whether and how the health implications of flexible work practices are considered in recent reviews of the Fair Work Act and the Modern Award Review Process. The research fills a policy vacuum in relation to the health impacts of the temporalities of working life, and will contribute to understanding time as both a cultural and economic resource. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100068
Funder
Australian Research Council
Funding Amount
$240,000.00
Summary
Mass spectrometry platform for high throughput genotyping, epigenetic analysis and validation of genome wide sequencing studies. This facility will provide a platform for Australian researchers to quantitatively measure genetic information in a rapid, accurate and cost-efficient manner. This technology will enhance Australia's ability to perform basic research into the genetic and epigenetic mechanisms of cellular function.
Islam and identity in Java: the violent culmination and subsequent decline of communal conflict, c. 1920- present. This project analyses for the first time the culmination of politicised and bloody conflict along lines of Islamic religious identity within Javanese society - today 100-million strong and Indonesia's largest ethnic group - and the subsequent decline and depoliticisation of those religiously defined categories, c. 1920-present. This process has left Javanese society more deeply Isla ....Islam and identity in Java: the violent culmination and subsequent decline of communal conflict, c. 1920- present. This project analyses for the first time the culmination of politicised and bloody conflict along lines of Islamic religious identity within Javanese society - today 100-million strong and Indonesia's largest ethnic group - and the subsequent decline and depoliticisation of those religiously defined categories, c. 1920-present. This process has left Javanese society more deeply Islamised than at any time in its history. But conflicting categories might, in theory, be repoliticised. The 2004 election campaign will be crucial for this analysis. The resultant book will be the last of three analysing the Islamisation of the Javanese from the 14th century to the present.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100141
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
High-resolution ITRAX XRF core scanning facility for global change research. This facility will enable researchers to obtain high-resolution geochemical profiles in the study of environmental change and climate variability. It will provide archive data on the variation of density and chemical element composition along sediment and soil cores, rock cores, wood samples, speleothems and corals. These archives contain important information such as human activity, climate variability, water quality c ....High-resolution ITRAX XRF core scanning facility for global change research. This facility will enable researchers to obtain high-resolution geochemical profiles in the study of environmental change and climate variability. It will provide archive data on the variation of density and chemical element composition along sediment and soil cores, rock cores, wood samples, speleothems and corals. These archives contain important information such as human activity, climate variability, water quality changes, pollution histories, recent geomorphological change, land-use change, introduction of invasive species and the occurrence of bushfires. A better understanding of the occurrence and timing of these major environmental issues is of national and regional importance.Read moreRead less
Improving Indigenous health and wellbeing over the family life course. Improving Indigenous health and wellbeing over the family life course. This project aims to reduce Indigenous health inequalities, a major social and economic problem, by improving the policy relevant evidence base on the determinants of Indigenous health and wellbeing. This project will compare the impact of the family life course on the health and wellbeing of Indigenous and non-Indigenous mothers and children. It will use ....Improving Indigenous health and wellbeing over the family life course. Improving Indigenous health and wellbeing over the family life course. This project aims to reduce Indigenous health inequalities, a major social and economic problem, by improving the policy relevant evidence base on the determinants of Indigenous health and wellbeing. This project will compare the impact of the family life course on the health and wellbeing of Indigenous and non-Indigenous mothers and children. It will use survey data that follows them over time to: 1) identify family structures that enhance or harm health and wellbeing, and; 2) track changes in health and wellbeing before, during and after family transitions (i.e. births, relationship changes). Anticipated results are better targeted policy interventions to reduce Indigenous health inequalities.Read moreRead less
Violence, Religion and Well-being in Contemporary Burma (Myanmar): A Medical Anthropological Study of Everyday Life Under Dictatorship. For 40 years, Burma has been controlled by a military dictatorship with human rights abuses occurring daily. Terror and political violence are used as tools of repression. An in-depth ethnographic study will be conducted into the relationship between emotional/psychological distress and the violence and fear that pervades everyday Burmese life. The project will ....Violence, Religion and Well-being in Contemporary Burma (Myanmar): A Medical Anthropological Study of Everyday Life Under Dictatorship. For 40 years, Burma has been controlled by a military dictatorship with human rights abuses occurring daily. Terror and political violence are used as tools of repression. An in-depth ethnographic study will be conducted into the relationship between emotional/psychological distress and the violence and fear that pervades everyday Burmese life. The project will test the hypothesis that religion plays an important role in mediating responses to fear. No other study has been conducted of everday life under this dictatorship, or of survival strategies created to alleviate fear. Outcomes will include refereed articles, a major monograph on the subject and the development of a new methodology appropriate for aiding victims of terror and torture.Read moreRead less
Adaptive Evolution of BRCA1 in Ancestral Mammals. This project investigates adaptive evolution of BRCA1 in the early radiation of mammals. We will test the hypothesis that the evolution of mammary glands and X chromosome inactivation has resulted in modification of the BRCA1 protein sequence as it aquired new roles in these processes. We will also investigate the importance of these changes inducing compensatory changes in other parts of the protein.