A Study To Investigate Alternative Regimens For Pneumococcal Vaccination Of Infants In A Developing Country
Funder
National Health and Medical Research Council
Funding Amount
$1,622,210.00
Summary
Streptococcus pneumoniae (Pnc) is the leading vaccine preventable cause of serious infection in infants. The current Pnc conjugate vaccine is very expensive (approximately USD $200-infant) so it is unlikely to be affordable for most developing countries. Moreover, as health care access in developing countries may be episodic and unreliable, many children do not receive either complete or timely vaccine courses. Therefore, it is important to investigate affordable and flexible ways to deliver thi ....Streptococcus pneumoniae (Pnc) is the leading vaccine preventable cause of serious infection in infants. The current Pnc conjugate vaccine is very expensive (approximately USD $200-infant) so it is unlikely to be affordable for most developing countries. Moreover, as health care access in developing countries may be episodic and unreliable, many children do not receive either complete or timely vaccine courses. Therefore, it is important to investigate affordable and flexible ways to deliver this vaccine, which are safe and effective. A recent WHO-GAVI meeting to address impediments to the introduction of these vaccines in developing countries recognized the need to evaluate other regimens of Pnc conjugate vaccine as an important research priority. This study has been deliberately formulated with that need in mind. The site for this research is Fiji. Although health services are good, Pnc disease, particularly pneumonia, remains the commonest cause of childhood morbidity and mortality. Fiji has good vaccine coverage and was the first Pacific country to introduce Hib vaccine. The arrival of the new, expensive Pnc conjugate vaccine presents a dilemma for Fiji and many similar countries. The expense of this vaccine would consume a large portion of the health budget. This study has two components: 1. A Phase 2 immunogenicity study (involving 750 infants) to evaluate regimens using reduced numbers of doses of Pnc conjugate vaccine, and using timing of dosing and combinations with the Pnc polysaccharide (PS) vaccine that may be more suited to the epidemiology of Pnc disease in developing countries. 2. An epidemiological study will measure the burden of invasive Pnc disease and pneumonia in Fiji. This will be part of a global effort to address these issues, and will be used to develop rapid assessment tools for these diseases in developing countries. We will seek cofounding for this component.Read moreRead less
Understanding recent Australian trends in alcohol consumption and harms. This project aims to provide critical insight into recent trends in alcohol consumption and related harm in Australia. Many indicators of harm from alcohol have increased dramatically in the past decade, while drinking behaviours appear largely unchanged. This project aims to investigate two potential explanations for these trends: that apparent increases in rates of alcohol-related harm are driven by operational or adminis ....Understanding recent Australian trends in alcohol consumption and harms. This project aims to provide critical insight into recent trends in alcohol consumption and related harm in Australia. Many indicators of harm from alcohol have increased dramatically in the past decade, while drinking behaviours appear largely unchanged. This project aims to investigate two potential explanations for these trends: that apparent increases in rates of alcohol-related harm are driven by operational or administrative practices rather than by increases in actual harm; and that stable per-capita consumption data obscures divergent drinking behaviours, with increases among heavy drinkers driving increasing harm rates. The project aims to inform alcohol policy debates, which rely on robust trend data.Read moreRead less
Emerging from the shadows: the evaluation of intervention strategies to reduce social isolation amongst the aged. Social isolation imposes a high cost on affected individuals and the community at large. This project will determine what interventions work in addressing social isolation amongst the older population.
From entitlement to experiment: The new governance of welfare to work. This project aims to model and explain the governance dynamics of welfare to work in Australia, New Zealand and the United Kingdom. Australia regularly undertakes major governance reforms in providing welfare to the unemployed and other groups in need. In this dynamic environment, welfare agencies are struggling to deliver benefits to the most disadvantaged people. Services must balance the need to meet central performance re ....From entitlement to experiment: The new governance of welfare to work. This project aims to model and explain the governance dynamics of welfare to work in Australia, New Zealand and the United Kingdom. Australia regularly undertakes major governance reforms in providing welfare to the unemployed and other groups in need. In this dynamic environment, welfare agencies are struggling to deliver benefits to the most disadvantaged people. Services must balance the need to meet central performance requirements against the desire to help clients. The project aims to create a new framework for understanding how policy instruments and design experiments can improve services for those who are in need.Read moreRead less
The new digital governance of welfare to work. This project aims to analyse the implementation of a 'digital first' employment services system, its effects on frontline services and governance, and its potential for policy learning. It expects to generate new knowledge on how digitalisation changes interactions between jobseekers, providers, employers and the government, by working with our industry partners in a collaborative innovation lab. Expected outcomes of this project include a theoretic ....The new digital governance of welfare to work. This project aims to analyse the implementation of a 'digital first' employment services system, its effects on frontline services and governance, and its potential for policy learning. It expects to generate new knowledge on how digitalisation changes interactions between jobseekers, providers, employers and the government, by working with our industry partners in a collaborative innovation lab. Expected outcomes of this project include a theoretically informed, and practically tested, model of how digitalisation can promote service design and policy innovation that benefits jobseekers and employers. This should provide significant benefits for welfare system design, service outcomes, and policy learning nationally and internationally. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100221
Funder
Australian Research Council
Funding Amount
$367,000.00
Summary
Linked Data PolicyHub Stage II: Urban & Regional Planning & Communications. Linked data policy hub stage II: urban and regional planning and communications:
This project aims to build on existing investments in open access knowledge infrastructure to develop collections of policy documentation and data and new tools for problem solving and analysis. Australia's ability to respond effectively to future economic, social and environmental challenges depends on our national capacity to develop and ....Linked Data PolicyHub Stage II: Urban & Regional Planning & Communications. Linked data policy hub stage II: urban and regional planning and communications:
This project aims to build on existing investments in open access knowledge infrastructure to develop collections of policy documentation and data and new tools for problem solving and analysis. Australia's ability to respond effectively to future economic, social and environmental challenges depends on our national capacity to develop and implement efficient and effective public policy. By enabling efficient universal access to historical and archived policy material, the project aims to provide critical research infrastructure that supports innovative approaches to Australian public policy research. This is expected to affect areas such as urban and regional community development and sustainability, planning and design of built and natural environments, infrastructure development, communications, and social and economic innovation.Read moreRead less
Increasing innovation and flexibility in social service delivery. This project will use a comparative methodology to investigate how contracted social services require careful regulation to ensure service effectiveness and improved organisational capacity. The outcome will include a practice model for understanding the relationship between regulation, contract structure and forms of service delivery innovation.
Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessmen ....Financing aged care in Australia: Mitigating fiscal gaps and maintaining intergenerational equity. Aged care has been identified as a significant contributor to the growing fiscal problems predicted for Australian government finances during the next 10 to 20 years. This project will develop the cutting-edge modelling tools needed to allow Australia to make informed decisions about possible reforms in aged care financing. It will create significant national benefits by allowing detailed assessment of the distributional impact of a wide range of possible reforms, including how the outcomes of any policy change will affect disadvantaged sections of our society, whether different generations will be fairly treated, and the impact by gender.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668334
Funder
Australian Research Council
Funding Amount
$158,844.00
Summary
Australian Policy Online Development Project. Australian Policy Online provides easy access to a large selection of research reports, papers and articles from centres and institutes throughout Australia. In 2006, the scope of APO's listings and its related research resources will be significantly broadened, increasing the value of the site to its users, including researchers in universities and the public service, journalists, teachers and students. Australia's relations with its neighbours in S ....Australian Policy Online Development Project. Australian Policy Online provides easy access to a large selection of research reports, papers and articles from centres and institutes throughout Australia. In 2006, the scope of APO's listings and its related research resources will be significantly broadened, increasing the value of the site to its users, including researchers in universities and the public service, journalists, teachers and students. Australia's relations with its neighbours in Southeast Asia will be a particular focus of this expansion, and the APO Briefings series of short, topical books will provide an additional, innovative publishing option for researchers. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989700
Funder
Australian Research Council
Funding Amount
$175,000.00
Summary
The Australian Policy Online Full-Text Research Repository and Thematic Gateways. By bringing together the research outputs of over 160 member centres and institutes, as well as selected material from government and other sources, Australian Policy Online (APO) makes a significant contribution to the national research effort across all National Research Priorities - environmental sustainability, promoting and maintaining good health, frontier technologies and safeguarding Australia - and to the ....The Australian Policy Online Full-Text Research Repository and Thematic Gateways. By bringing together the research outputs of over 160 member centres and institutes, as well as selected material from government and other sources, Australian Policy Online (APO) makes a significant contribution to the national research effort across all National Research Priorities - environmental sustainability, promoting and maintaining good health, frontier technologies and safeguarding Australia - and to the development of well-informed public policy. This project will increase the value of APO by deepening its coverage of preventative health, planning and the environment, and citizenship; broadening its collection of research material; and offering new resources for researchers.Read moreRead less