A Transmission-Blocking Vaccine To Prevent Toxoplasmosis
Funder
National Health and Medical Research Council
Funding Amount
$850,225.00
Summary
Toxoplasma gondii causes a globally important zoonotic disease. It is transmitted by cats, and finds its way into our food chain via infected meat and contaminated water. We have used a unique functional genomics pipeline to discover proteins crucial for reproduction of Toxoplasma in the cat. We will now test combinations of these proteins to immunise cats and prove that we can develop a vaccine that blocks transmission of this highly significant parasitic disease.
The Role Of Capsid Protein Nucleolar Localisation In Chikungunya Virus: Implications For Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$520,520.00
Summary
Chikungunya virus (CHIKV) is a globally widespread mosquito-borne alphavirus capable of causing considerable human morbidity and mortality. With no CHIKV vaccine or antiviral available this proposal aims to develop a live attenuated CHIKV vaccine, rationally designed by investigating the host cell nucleolar trafficking of CHIKV capsid protein. This vaccine has the potential to provide cross-protection against additional arthritogenic alphaviruses endemic to Australia such as Ross River virus.
Amplifying Indigenous news: a digital intervention. This project aims to road-test, document and analyse an innovative strategy for amplifying Indigenous voices in news media. The project will deploy and assess the impact of a new digital application designed to enable access to a diverse range of Indigenous voices, stories and agendas. The anticipated outcomes will assist the project’s industry partners meet their strategic goals of increasing the level of Indigenous media representation in Aus ....Amplifying Indigenous news: a digital intervention. This project aims to road-test, document and analyse an innovative strategy for amplifying Indigenous voices in news media. The project will deploy and assess the impact of a new digital application designed to enable access to a diverse range of Indigenous voices, stories and agendas. The anticipated outcomes will assist the project’s industry partners meet their strategic goals of increasing the level of Indigenous media representation in Australia, and consolidate their roles as leading outlets for Indigenous content and coverage. These outcomes are also expected to improve public understanding of issues affecting Indigenous Australians and contribute to more informed and inclusive policy discussions.Read moreRead less
Mobile Indonesians: social differentiation and digital literacies in the twenty first century. This is the first dedicated study of the social implications of mobile telephony's recent and rapid popularisation throughout the country. This project will study metropolitan, urban and rural users to understand how mobile phones create the new and unexpected social networks which will shape tomorrow's Indonesians.
Valuing News: Aligning Individual, Institutional and Societal Perspectives. This project aims to identify the links between the preparedness of individuals to pay for news, the value of news brands and organisational cultures of news publishers, and the social value of news in promoting a democratic public sphere. Its significance arises with the ongoing crisis of news media business models, which is raising new questions about the future of journalism, and the changing role of governments worl ....Valuing News: Aligning Individual, Institutional and Societal Perspectives. This project aims to identify the links between the preparedness of individuals to pay for news, the value of news brands and organisational cultures of news publishers, and the social value of news in promoting a democratic public sphere. Its significance arises with the ongoing crisis of news media business models, which is raising new questions about the future of journalism, and the changing role of governments worldwide in financing news production. Its expected outcomes include advancing debates about how to support public interest journalism, and the value of news as both a commodity and a public good. It will be of benefit to industry, policymakers and the community in addressing the prospects for Australian journalism. Read moreRead less
Intercultural inquiry in a trans-national context: Exploring the legacy of the 1948 American-Australian Scientific Expedition to Arnhem Land. In terms of National Research Priorities, the project will encourage cultural health and cohesiveness in Arnhem Land by providing access to cultural property held until now in remote archives. It will enhance understanding of our region and the world by studying cross-cultural interactions within Australia. Furthermore, it will illuminate how Aboriginal te ....Intercultural inquiry in a trans-national context: Exploring the legacy of the 1948 American-Australian Scientific Expedition to Arnhem Land. In terms of National Research Priorities, the project will encourage cultural health and cohesiveness in Arnhem Land by providing access to cultural property held until now in remote archives. It will enhance understanding of our region and the world by studying cross-cultural interactions within Australia. Furthermore, it will illuminate how Aboriginal territory and knowledge were used to shore up the Australia-US relationship at a formative historical moment.Read moreRead less
Expedition to Arnhem Land: Intercultural inquiry in a trans-national context. In terms of National Research Priorities, the project will encourage cultural health and cohesiveness in Arnhem Land by providing access to cultural property held until now in remote archives. It will enhance understanding of our region and the world by studying cross-cultural interactions within Australia. Furthermore, it will illuminate how Aboriginal territory and knowledge were used to shore up the Australia-US rel ....Expedition to Arnhem Land: Intercultural inquiry in a trans-national context. In terms of National Research Priorities, the project will encourage cultural health and cohesiveness in Arnhem Land by providing access to cultural property held until now in remote archives. It will enhance understanding of our region and the world by studying cross-cultural interactions within Australia. Furthermore, it will illuminate how Aboriginal territory and knowledge were used to shore up the Australia-US relationship at a formative historical moment.Read moreRead less
Breaking silences: media and the Child Abuse Royal Commission. This project aims to analyse the role of media, journalism and social media activism in the Royal Commission into Institutional Responses to Child Sexual Abuse (2013-17) (RCIRCSA). By focusing on the nexus between media and commissions of inquiry in the digital era, the project will investigate the impacts of a rapidly changing media environment on this national 'listening' exercise. The project will use a case study approach to crit ....Breaking silences: media and the Child Abuse Royal Commission. This project aims to analyse the role of media, journalism and social media activism in the Royal Commission into Institutional Responses to Child Sexual Abuse (2013-17) (RCIRCSA). By focusing on the nexus between media and commissions of inquiry in the digital era, the project will investigate the impacts of a rapidly changing media environment on this national 'listening' exercise. The project will use a case study approach to critically analyse the role of a transitioning local, national and social media in triggering, reporting on and keeping alive the findings of the royal commission, ensuring victims of institutional child sexual abuse are heard, and justice is upheld.Read moreRead less
ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial ....ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial concepts into statistical analysis and modelling, powerful visualisation of information, and the building spatial decision support systems, to provide an improved evidence base and better informed decision-making to address the significant challenges facing Australia's people and its places.Read moreRead less
Heartbeat of Australia: Tracking, Understanding and Engaging News Audiences. This project aims to address the existential crisis of local news by developing a barometer of the health of local news ecosystems informed by longitudinal audience surveys, stakeholder in-depth interviews and case studies of marginalised audiences. Expected outcomes include a robust evidence base to assess the value of local news to audiences and wider society, and innovative new strategies to better address the challe ....Heartbeat of Australia: Tracking, Understanding and Engaging News Audiences. This project aims to address the existential crisis of local news by developing a barometer of the health of local news ecosystems informed by longitudinal audience surveys, stakeholder in-depth interviews and case studies of marginalised audiences. Expected outcomes include a robust evidence base to assess the value of local news to audiences and wider society, and innovative new strategies to better address the challenges the news industry faces in adapting to the digital environment. By devising strategies to produce and deliver quality local news that is financially sustainable, the project aims to deliver significant benefits to the news industry and the wellbeing of individuals and communities across Australia. Read moreRead less