Some infections can start inflammation that, while controlling the infection, can also attack the body tissues of genetically susceptible people. This inflammation can initiate long term problems including arthritis, diabetes and cancer. Our research program seeks to understand who is genetically at risk of this sort of problem and why, and thus to develop new means to prevent and treat the chronic diseases that are initiated in this way.
Atherosclerosis - The Key Roles Of HDL, Cell Cholesterol Metabolism And Vascular Function
Funder
National Health and Medical Research Council
Funding Amount
$7,085,050.00
Summary
Atherosclerosis, an accumulation of cholesterol in the artery wall, is a major cause of illness and premature death worldwide. It is caused by conditions such as low levels of the protective high density lipoproteins (HDLs), diabetes, smoking and abnormal function of arteries, all of which are linked to disorders of cholesterol metabolism. With our expertise in HDLs, cholesterol metabolism and artery function, our research will lead to the development of novel strategies for early detection and ....Atherosclerosis, an accumulation of cholesterol in the artery wall, is a major cause of illness and premature death worldwide. It is caused by conditions such as low levels of the protective high density lipoproteins (HDLs), diabetes, smoking and abnormal function of arteries, all of which are linked to disorders of cholesterol metabolism. With our expertise in HDLs, cholesterol metabolism and artery function, our research will lead to the development of novel strategies for early detection and prevention of atherosclerosis and heart disease.Read moreRead less