RNA-based analysis for prediction of islet death in diabetes. Death of insulin-producing cells is a common feature in diabetes. Presently, a blood glucose test remains the only blunt instrument to diagnose diabetes. The RNA-based analysis for prediction of islet death in diabetes (RAPID) study links with eight clinical trials to test this newly developed non-invasive assay for predicting diabetes. Early diagnosis will help to reduce diabetic complications in later life.
Discovery Early Career Researcher Award - Grant ID: DE180100090
Funder
Australian Research Council
Funding Amount
$386,831.00
Summary
The trouble with culture: Rationalizing Indigenous health inequality. This project aims to advance understanding of the importance of race in contemporary Indigenous public health discourse and practice. Using critical race theory, this project will illuminate our understanding of, and ability to address Indigenous health inequality and support the formulation of a race-critical Australia public health research agenda.
The effect of genomic variants on Indigenous health. The effect of genomic variants on Indigenous health. This project aims to examine the genetic variants introduced by Europeans (and other groups) into the genomes of the Aboriginal Australian population. The rate of metabolic diseases such as diabetes and hypertension is very high in Australia’s Indigenous populations. While an energy-rich Western diet has been suggested as the major cause, the contribution of genomic variants (mutations) rema ....The effect of genomic variants on Indigenous health. The effect of genomic variants on Indigenous health. This project aims to examine the genetic variants introduced by Europeans (and other groups) into the genomes of the Aboriginal Australian population. The rate of metabolic diseases such as diabetes and hypertension is very high in Australia’s Indigenous populations. While an energy-rich Western diet has been suggested as the major cause, the contribution of genomic variants (mutations) remains unclear. Anticipated outcomes are better understandings of both the benign and deleterious variants introduced into Aboriginal Australian populations and how these contribute to disease susceptibility.Read moreRead less
Serving our country: a history of Aboriginal and Torres Strait Islander people in the defence of Australia. This project researches the history of Aboriginal and Torres Strait Islander people in the defence of Australia. The project will provide authoritative accounts of their contributions to nation.
Discovery Indigenous Researchers Development - Grant ID: DI110100011
Funder
Australian Research Council
Funding Amount
$199,445.00
Summary
A whole-of-community approach to promoting engagement into education in a discrete Indigenous community: a mixed method study. This research will develop a whole-of-community approach to engage Indigenous learners with education and provide evidence of a model that works. Developed in one community, the model will contribute policy-relevant knowledge for improving Indigenous educational outcomes and meeting the Commonwealth Government's Closing the Gap targets.
Understanding how cells in the olfactory nerve prevent brain infection. The project hypothesis is that the phagocytic activity of olfactory ensheathing cells (OECs) is the key factor that prevents bacteria from accessing the brain via the olfactory nerve, and allows continuous regeneration of the olfactory nervous system. This project aims to investigate how OECs phagocytose bacteria and debris from degenerating axons in vivo, and determine key molecular mechanisms in the process. Thus, we will ....Understanding how cells in the olfactory nerve prevent brain infection. The project hypothesis is that the phagocytic activity of olfactory ensheathing cells (OECs) is the key factor that prevents bacteria from accessing the brain via the olfactory nerve, and allows continuous regeneration of the olfactory nervous system. This project aims to investigate how OECs phagocytose bacteria and debris from degenerating axons in vivo, and determine key molecular mechanisms in the process. Thus, we will characterise an unknown aspect of OEC biology that is neglected in the field. Intended outcomes include a paradigm shift that glial cells, and not circulatory immune cells, are the main defense against microbial invasion of the olfactory nerve. This is relevant for new therapies targeting neural infection/injury and antibiotic usage.Read moreRead less
Youth services in remote communities. This project aims to improve outcomes for high-risk youth in remote communities in Australia and Canada. It will establish a transdisciplinary research network comprising researchers and services experienced in delivering programmes to high-risk youth; develop a universal intervention definition, and a useful, scientifically rigorous evaluation framework; and integrate the intervention and evaluation framework into participating services’ routine service del ....Youth services in remote communities. This project aims to improve outcomes for high-risk youth in remote communities in Australia and Canada. It will establish a transdisciplinary research network comprising researchers and services experienced in delivering programmes to high-risk youth; develop a universal intervention definition, and a useful, scientifically rigorous evaluation framework; and integrate the intervention and evaluation framework into participating services’ routine service delivery. This project expects to increase the number and quality of services available for high-risk youth, improve their social, health and economic outcomes, and generate positive economic benefit for their communities.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100211
Funder
Australian Research Council
Funding Amount
$370,045.00
Summary
Improving alcohol prevention in Aboriginal and Torres Strait Islander drug and alcohol services. This project will work with the Aboriginal and Torres Strait Islander drug and alcohol sector in Queensland to develop and test a process for improving the delivery of alcohol prevention services.
Special Research Initiatives - Grant ID: SR120100005
Funder
Australian Research Council
Funding Amount
$3,198,392.00
Summary
National Indigenous Research and Knowledges Network. The National Indigenous Research and Knowledges Network will capacity build and increase Indigenous higher degree, early and mid career researchers to develop new approaches to undertaking research and producing outcomes. NIRAKN's members include a number of universities, AIATSIS, and partner organisations.
Strengthening Indigenous adolescent mental health and wellbeing. Using Continous Quality Improvement processes, the research will collaboratively conceptualise, design, implement and evaluate the effectiveness of new approaches to mental health service delivery for adolescents aged 10-24 in three regionally diverse Indigenous Primary Healthcare Services. Expected research outcomes are a rigorous assessment of the impact and economic benefits of making quality improvements to mental health servic ....Strengthening Indigenous adolescent mental health and wellbeing. Using Continous Quality Improvement processes, the research will collaboratively conceptualise, design, implement and evaluate the effectiveness of new approaches to mental health service delivery for adolescents aged 10-24 in three regionally diverse Indigenous Primary Healthcare Services. Expected research outcomes are a rigorous assessment of the impact and economic benefits of making quality improvements to mental health services for Indigenous adolescents, Key benefits are 1) A locally-responsive adolescent mental health screening instrument; 2) Comprehensive evidence-informed service model in adolescent mental healthcare; 3) Best practice protocol for developing and managing adolescent mental health as a service delivery stream. Read moreRead less