Investigating A Theoretical Model Of Cognitive Control In Children With Attention Deficit Hyperactivity Disorder (ADHD): Informing Our Approach To Cognitive Training.
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
ADHD is the most common childhood developmental disorder, characterised by inattentive and/or hyperactive behaviours. Cognitive control has been highlighted as a potential mediator of ADHD symptoms. This program will i) delineate the relationship between cognitive control and ADHD symptoms, ii) develop a cognitive training intervention to target the underlying mechanisms identified as mediators of ADHD symptoms and iii) evaluate the program in a gold-standard clinical trial.
The Burden And Risk Factors Of Depressive Disorders In Indigenous Australians: Implications For Early Detection And Prevention
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
This Fellowship addresses the high rates of depression amongst Indigenous Australians. The proposed work will quantify the extent to which two major risk factors contribute to the burden of depression in this population and the burden avertable from interventions to modify these risk factors. Findings would inform resource allocation and health service delivery, and in doing so, present opportunities for improvements in the health of Indigenous Australians.
Developing A Pathophysiological Model For Attention Deficit Hyperactivity Disorder: A Path To Biomarker Discovery
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
Despite the efficacy of stimulant medication in treating attention deficit hyperactivity disorder (ADHD), we lack mechanistic accounts of the neuropathology of ADHD. A major barrier is the lack of human disease models representing clinical symptoms. The derivation of a novel, cell-based ADHD model proposed in this project will shed new light on the physiological bases of ADHD and be a rich resource for biomarker discovery
Improving Visual Outcomes In Patients With Diabetic Macular Oedema Undergoing Cataract Surgery: A Prospective Randomised Clinical Trial (the DiMECat Trial)
Funder
National Health and Medical Research Council
Funding Amount
$187,322.00
Summary
Cataract and diabetic retinopathy are the leading causes of visual loss in patients with diabetes, but unfortunately, cataract surgery in these patients often results in a loss of vision, rather than an improvement. The purpose of this study is to improve the visual outcomes in this group of patients, through the use of new, injected medicines that are given at the time of cataract surgery, thereby potentially changing current medical practice.
Investigating Caloric Vestibular Stimulation As A Novel Therapeutic Intervention For Chronic Pain, Mania And Depression.
Funder
National Health and Medical Research Council
Funding Amount
$340,963.00
Summary
Chronic pain, mania and depression are common health problems worldwide and represent an enormous burden of illness. Current treatments may be costly, invasive and have serious side-effects. In the proposed project, demonstration of therapeutic benefit with a novel, simple method of brain stimulation without such limitations could change how these disorders are managed. Moreover, the findings would be of substantial significance in developing countries where treatments are often non-existent.
Improving Outcomes For Children With Common Developmental Conditions: Identifying Risk And Protective Factors And Developing Targeted Interventions
Funder
National Health and Medical Research Council
Funding Amount
$307,946.00
Summary
Attention Deficit Hyperactivity Disorder (ADHD) and language impairment (LI) are both highly prevalent and associated with mental health difficulties. This research will investigate 1) risk factors for poor versus better mental health, academic and social outcomes in children with ADHD and LI and 2) the development and piloting of interventions targeting these factors. This research will indicate avenues for new methods of intervention and prevention for children with ADHD and LI.
Novel Morphological Retinal Vascular Features As Early Biomarkers Of Vision-threatening Eye Diseases.
Funder
National Health and Medical Research Council
Funding Amount
$107,169.00
Summary
Vision loss is not just a personal health burden, but a huge socio-economical burden. Management of major vision-threatening eye diseases such as diabetic retinopathy, age-related macular degeneration and glaucoma will be improved if we can successfully identified persons at risk of developing the disease before clinical presentation to benefit from preventive treatment. My research aims to contribute to the prediction of these blinding diseases using advanced computer imaging analysis for simpl ....Vision loss is not just a personal health burden, but a huge socio-economical burden. Management of major vision-threatening eye diseases such as diabetic retinopathy, age-related macular degeneration and glaucoma will be improved if we can successfully identified persons at risk of developing the disease before clinical presentation to benefit from preventive treatment. My research aims to contribute to the prediction of these blinding diseases using advanced computer imaging analysis for simple retinal photographs.Read moreRead less