Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Neural circuit control of effort under stress . This Project aims to investigate how the ‘decision’ to persist in exerting effort to obtain a reward is encoded in the the brain and affected by stress. This work will generate new knowledge on the neural mechanisms through which stress modifies neural activity to control decision making processes underpinning adaptive behaviours essential for survival. The expected outcomes of this work include enhanced capacity at the interface of behavioural a ....Neural circuit control of effort under stress . This Project aims to investigate how the ‘decision’ to persist in exerting effort to obtain a reward is encoded in the the brain and affected by stress. This work will generate new knowledge on the neural mechanisms through which stress modifies neural activity to control decision making processes underpinning adaptive behaviours essential for survival. The expected outcomes of this work include enhanced capacity at the interface of behavioural and computational neuroscience, that will in turn provide significant benefits through greater insight into brain functions essential for survival, with long ranging implications for performance optimisation and brain-inspired computing. Read moreRead less
ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision system ....ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision systems with applications in industry and national security. Other knowledge will develop novel diagnostic technologies, for application in health delivery.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668246
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Advanced Cell Labelling and Imaging Facility. Understanding the genetic regulation of cellular processes such as migration, differentiation and growth is an important frontier technology with significant biomedical potential. The Australian community is facing an increasing need to provide solutions for a variety of human diseases and disorders, including birth defects, nervous system injury and stroke, and ageing-related conditions. The proposed facility will allow researchers to test in vivo g ....Advanced Cell Labelling and Imaging Facility. Understanding the genetic regulation of cellular processes such as migration, differentiation and growth is an important frontier technology with significant biomedical potential. The Australian community is facing an increasing need to provide solutions for a variety of human diseases and disorders, including birth defects, nervous system injury and stroke, and ageing-related conditions. The proposed facility will allow researchers to test in vivo gene/pharmaceutical therapies as well as to better understand the genetic regulation of normal cellular processes. Read moreRead less
Investigating the role of the innate immune complement system in the abnormal development of the central nervous system. Past research has discovered a surprising link between the immune system, dietary folate deficiency and the development of the embryonic brain. This project will investigate the immune system in the developing brain, in order to understand the causes of developmental defects such as neural tube defects, and the role dietary folate plays in this process.
Airports of the Future. This project will enhance the capabilities of Australian airport operators to design and manage complex airport systems. Research outcomes will enable the identification of patterns of behaviour and will provide tools to manage airport effectiveness and balance conflicting security, economic and passenger-driven pressures. Outcomes will improve productivity, enhance capabilities for critical infrastructure protection, and lessen the cost of mandated security, estimated t ....Airports of the Future. This project will enhance the capabilities of Australian airport operators to design and manage complex airport systems. Research outcomes will enable the identification of patterns of behaviour and will provide tools to manage airport effectiveness and balance conflicting security, economic and passenger-driven pressures. Outcomes will improve productivity, enhance capabilities for critical infrastructure protection, and lessen the cost of mandated security, estimated to grow to $152M by 2010 for the five major Australian airports. The deliverables of this project will be transferable to other complex socio-technical systems providing the potential to transform a range of Australian critical infrastructure and transportation hubs.Read moreRead less
ARC Research Network for Enabling Human Communication. The Human Communication Network promotes interdisciplinary research in speech, language, and sound by and between humans and machines. The network connects leading and emerging researchers across disciplines, exploits previously unrecognised intersections, supports interdisciplinary graduate training and exchanges, provides database storage infrastructure, and consults with industry and government to set, not follow, research agendas. By ge ....ARC Research Network for Enabling Human Communication. The Human Communication Network promotes interdisciplinary research in speech, language, and sound by and between humans and machines. The network connects leading and emerging researchers across disciplines, exploits previously unrecognised intersections, supports interdisciplinary graduate training and exchanges, provides database storage infrastructure, and consults with industry and government to set, not follow, research agendas. By generating an explosion of new approaches and knowledge, the network will build Australia's reputation as a leader in communication science and technology via advances in automatic speech recognition, distress call monitoring, hearing prostheses, web interfaces, and data retrieval and data mining systems.Read moreRead less
Special Research Initiatives - Grant ID: SR120300015
Funder
Australian Research Council
Funding Amount
$16,000,000.00
Summary
The Science of Learning Research Centre. In this innovative new Centre, researchers in education, neuroscience and cognitive psychology will work together with teachers to understand the learning process. This collaboration will establish new criteria to assess the impact of different types of learning and strategies to inform teaching practices of benefit to all Australians.
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
ARC Centre of Excellence for Robotic Vision. Robots are vital to Australia's future prosperity in the face of high relative wages, low or decreasing productivity, and impending labour shortages. However the work and workplaces of our most important industries are unstructured and changeable and current robots are challenged by their inability to quickly, safely and reliably "see" and "understand" what is around them. The Centre's research will create the fundamental science and technologies th ....ARC Centre of Excellence for Robotic Vision. Robots are vital to Australia's future prosperity in the face of high relative wages, low or decreasing productivity, and impending labour shortages. However the work and workplaces of our most important industries are unstructured and changeable and current robots are challenged by their inability to quickly, safely and reliably "see" and "understand" what is around them. The Centre's research will create the fundamental science and technologies that will allow robots to see as we do, and overcome the last barrier to the ubiquitous deployment of robots into society for the benefit of all.Read moreRead less