Investigating The Mechanisms Underpinning The Dynamic Vessel Response In People With Diabetic Retinopathy
Funder
National Health and Medical Research Council
Funding Amount
$18,808.00
Summary
Endothelial dysfunction has been well-hypothesised as one of the key players in the pathogenesis of DR. However, there is strong evidence suggesting a neurovascular coupling mechanism in the retinal circulation during flicker. It is therefore unclear whether reduced flicker light induced vasodilation observed in diabetes and DR is associated with endothelial dysfunction, an impairment of neurovascular coupling or both. This project aims to address this important knowledge gap.
Investigating Trans-synaptic Degeneration In The Human Visual Pathway
Funder
National Health and Medical Research Council
Funding Amount
$79,514.00
Summary
This research project investigates the spread of neuronal damage along the visual pathway from the retina to higher order areas including the visual cortex and inter-hemispheric tracts. This trans-synaptic degeneration will be examined in Leber's optic atrophy, optic neuritis and glaucoma.