Neourobiology Of Human Epilepsy: Genes, Cellular Mechanisms,network And Whole Brain
Funder
National Health and Medical Research Council
Funding Amount
$17,652,824.00
Summary
The team is comprised of neurologists, molecular geneticists, physiologists and brain imaging specialists and leads the world in the discovery of the genetic causes of epilepsy. They will continue to identify genes underlying epilepsy and study how genetic variations result in development of seizures. Advanced brain imaging will be used to understand the effects of genetic variation on brain structure and function. This study may lead to new diagnostic methods and treatments for epilepsy.
A Longitudinal Study Of Psychopathology In People With Intellectual Disability
Funder
National Health and Medical Research Council
Funding Amount
$999,803.00
Summary
This project will further develop the research opportunities of an internationally unique 15 year follow up study of the mental health of young Australians with ID. We have shown that this group has 2-3 times the risk of suffering serious emotional and behavioural problems that are an added heavy burden on the individual, their family and carers and the community. These problems often are not recognised but are as common as schizophrenia in the community. The study will continue to use a combina ....This project will further develop the research opportunities of an internationally unique 15 year follow up study of the mental health of young Australians with ID. We have shown that this group has 2-3 times the risk of suffering serious emotional and behavioural problems that are an added heavy burden on the individual, their family and carers and the community. These problems often are not recognised but are as common as schizophrenia in the community. The study will continue to use a combination of questionnaire survey and in depth interviews of the young adults and their families or carers to track the course of their mental health. The study commenced in 1990 with nearly 1000 young people with ID aged 4-18 years and their progress has been reviewed every 2-3 years in over 75% of the original group. During the next 5 years we plan to follow their mental health during the critical stage of young adult life. During this time there is the greatest risk of mental illnesses such as depression and schizophrenia and the stresses of adjusting to new daily occupations, independent living or residential care and social contact away from the family. We will be able to study the specific emotional and behavioural problems faced by young adults with the main known causes of ID such as Down, Fragile X, Prader Willi and William Syndromes, as well as those who have autism. The great benefit of a long term follow up study is that it allows us to study the links between earlier family environmental, psychological and biological factors and subsequent mental health problems. We can also demonstrate the impact that mental illness in a young person with ID has on the family and parental mental health. The findings have implications for better diagnosis, improved care and management, early intervention and prevention of these common severe and under recognized mental health problems in this disadvantaged group of young Australians and their families and carers.Read moreRead less
Using 3D printing to improve access to graphics by vision-impaired people. This project aims to investigate the possible benefits of 3D printing for production of accessible materials for vision-impaired people. Currently tactile graphics are used to provide severely vision-impaired adults and children with access to graphical content used in education and in orientation and mobility training. This project is expected to clarify the kinds of graphics for which 3D prints are better suited than ta ....Using 3D printing to improve access to graphics by vision-impaired people. This project aims to investigate the possible benefits of 3D printing for production of accessible materials for vision-impaired people. Currently tactile graphics are used to provide severely vision-impaired adults and children with access to graphical content used in education and in orientation and mobility training. This project is expected to clarify the kinds of graphics for which 3D prints are better suited than tactile graphics, and to build capacity within the national accessible format provision sector for the production and use of 3D prints. Benefits will include increased educational opportunities and quality of life for Australians with severe vision impairment, through improved access to graphic materials used in education and orientation and mobility training.
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International Managers: How Do We Get Them? Explanations of Staffing Strategy for International Work Performed From Home or Abroad. Australian companies often need to expand globally to survive and prosper. Yet, they report a shortage of managers for international work. This project aims to explain how companies staff international work, conceived as a set of interrelated options in which the work may be performed abroad or domestically from Australia. International staffing has rarely been ....International Managers: How Do We Get Them? Explanations of Staffing Strategy for International Work Performed From Home or Abroad. Australian companies often need to expand globally to survive and prosper. Yet, they report a shortage of managers for international work. This project aims to explain how companies staff international work, conceived as a set of interrelated options in which the work may be performed abroad or domestically from Australia. International staffing has rarely been considered as a comprehensive set of alternatives. This project will explain staffing strategy from organisational and individual perspectives and factors, including why women are underrepresented. The results will help understand the staffing strategy, management development, retention, and equity practices needed to staff international work.Read moreRead less
Research Utilisation in Child Protection Policy: Understanding and Conceptualising the Role of Research in Social Policy Development. The findings of this project will have significant benefits for vulnerable children and families by enhancing the capacity for research-informed policy in child protection. In this way, the project will also have significant flow-on economic benefits for Local, State and Federal Governments by decreasing the social and economic costs associated with child abuse an ....Research Utilisation in Child Protection Policy: Understanding and Conceptualising the Role of Research in Social Policy Development. The findings of this project will have significant benefits for vulnerable children and families by enhancing the capacity for research-informed policy in child protection. In this way, the project will also have significant flow-on economic benefits for Local, State and Federal Governments by decreasing the social and economic costs associated with child abuse and neglect. Research funding will have a greater impact by the increased understanding this study will provide about how research can be more effectively used in policy.Read moreRead less
Factors associated with the recruitment and retention of the current and future nursing workforce - a longitudinal e-cohort study. The overall effectiveness of the Australian health care system is dependent on a knowledgeable, skilled and viable nursing workforce. Currently there is a critical shortage of qualified nurses actively working in the Australian health care system which limits the capacity of the system to effectively manage an ageing population. The broad aim of this research project ....Factors associated with the recruitment and retention of the current and future nursing workforce - a longitudinal e-cohort study. The overall effectiveness of the Australian health care system is dependent on a knowledgeable, skilled and viable nursing workforce. Currently there is a critical shortage of qualified nurses actively working in the Australian health care system which limits the capacity of the system to effectively manage an ageing population. The broad aim of this research project is to examine factors associated with recruitment and retention of the current and future nursing workforce across metropolitan, regional and rural areas; with a particular focus on work-based injury. In addition, the project will employ smart use of information technology to develop innovative e-cohort techniques.Read moreRead less
Creating and sustaining a strong future for volunteering in Australia. This project seeks to answer the question of how to increase social participation by converting non-volunteers to the benefits of volunteering. In Australia today, communities and governments are increasingly dependent on volunteers to build social capital and deliver an increasing range of services. A world first, this project aims to create new theory by examining three levels of analysis: the micro level of the individual ....Creating and sustaining a strong future for volunteering in Australia. This project seeks to answer the question of how to increase social participation by converting non-volunteers to the benefits of volunteering. In Australia today, communities and governments are increasingly dependent on volunteers to build social capital and deliver an increasing range of services. A world first, this project aims to create new theory by examining three levels of analysis: the micro level of the individual volunteer or non-volunteer; the mezzo level of the volunteer-involving organisation; and the macro level of society. This innovative approach aims to identify, analyse and develop a tool to help organisations build Australia’s civil society and develop policy to create a sustainable volunteer sector into the future.Read moreRead less
The importance of gender and socio-economic disadvantage for the mental health of people living with disabilities. The twenty per cent of Australians reporting a disability are more likely to live in disadvantaged circumstances such as inadequate housing, unemployment, and lower levels of education all of which may contribute to poor mental health. Yet there has not been research on the mental health of people with disabilities. This means that disability services and advocacy groups, which deal ....The importance of gender and socio-economic disadvantage for the mental health of people living with disabilities. The twenty per cent of Australians reporting a disability are more likely to live in disadvantaged circumstances such as inadequate housing, unemployment, and lower levels of education all of which may contribute to poor mental health. Yet there has not been research on the mental health of people with disabilities. This means that disability services and advocacy groups, which deal daily with the lived experiences of disadvantage and poor mental health in people with disabilities, do not have evidence to support policy and service sector reform. This project will provide this critical evidence as well as build research capacity in disability-related research and lead to better monitoring of disability-related health inequities.Read moreRead less
Left to right is front to back: attentional distortions in near and far space for healthy and clinical populations. We are investigating a perceptual bias that makes people think objects right in front of them are actually slightly to the right but objects far away are slightly to the left. This project will help understand why this happens, to help reduce traffic collisions and help people with brain damage that causes similar perceptual biases.
Recruitment and Retention of the Australian Medical Practitioner Workforce - a Longitudinal Electronic Cohort Study. Identifying and acknowledging the significant personal and professional influences on the career decisions of doctors, including the choice to leave the profession for several years and factors driving the decision to return or not return, will provide not only the major public employers of doctors, but also government, community and private practice groups with reliable current e ....Recruitment and Retention of the Australian Medical Practitioner Workforce - a Longitudinal Electronic Cohort Study. Identifying and acknowledging the significant personal and professional influences on the career decisions of doctors, including the choice to leave the profession for several years and factors driving the decision to return or not return, will provide not only the major public employers of doctors, but also government, community and private practice groups with reliable current evidence to inform medical workforce planning and design, and ensure quality health care. Read moreRead less