Discovery Projects - Grant ID: DP0212084

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP0212084

Funding Status
Closed

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Funded Activity Summary

Modulation of cellular metabolism by protein and peptide peroxides. Oxidation of peptides and proteins by a wide range of reactive radicals and other oxidants, in the presence of oxygen, generates protein peroxides. These species are now recognised to be key intermediates in both the deterioration of foods (e.g. development of rancidity and off-flavours, changes in colour and texture) and a number of human diseases, including cancer, heart disease and ageing. How these peroxides cause biological perturbations is poorly understood. The proposed studies will provide valuable information as to how these peroxides affect cellular metabolism and provide key leads as to strategies which may prevent such damage.

Funded Activity Details

Start Date: 01-01-2002

End Date: 31-12-2004

Funding Scheme: Discovery Projects

Funding Amount: $248,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Enzymes | Biochemistry and Cell Biology | Biological And Medical Chemistry | Analytical Biochemistry |

ANZSRC Socio-Economic Objective (SEO)

Biological sciences | Chemical sciences

Other Keywords

Analytical Biochemistry | Biochemistry and Cell Biology | Biological And Medical Chemistry | Biological sciences | Chemical sciences | Enzymes

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