Discovery Projects - Grant ID: DP0450122

Funding Activity

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Funded Activity Summary

Probing and Developing Hypoxia-Selective Anti-Cancer Agents. The development of compounds that are effective in the treatment of cancer and are less toxic than existing drugs depends on the selective targeting of tumours. Solid tumours have poorly oxygenated regions which represent unique chemical environments that can be targeted using selectively activated compounds. In this project we will develop the first in situ methods for monitoring the activation state in solid tumours to establish the selectivity of activation. These results will be used to tune the properties of two novel classes of selectively activated compounds and thereby develop agents able to treat the most problematic of cancers.

Funded Activity Details

Start Date: 01-02-2004

End Date: 31-12-2006

Funding Scheme: Discovery Projects

Funding Amount: $240,000.00

Funder: Australian Research Council