Discovery Projects - Grant ID: DP140100240

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP140100240

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Polyion complex micelles as smart nano-sized drug carriers for proteins. Novel treatments against diseases are often based on proteins, which are unstable against hydrolysis and sometimes difficult to deliver across the cell membrane. The aim of the project is to create a smart drug carrier that can encapsulate proteins efficiently. A range of block copolymers will be synthesised that are able to condense a positively charged protein resulting in the formation of polyion complex micelles. The polymer structure will be fine-tuned to create a drug carrier that releases the protein efficiently once inside mammalian cells. The outcome will be the enhanced understanding of the relationship between polymer structure and the activity of the protein and ultimately the design of an advanced and smart drug carrier.

Funded Activity Details

Start Date: 01-01-2014

End Date: 21-12-2017

Funding Scheme: Discovery Projects

Funding Amount: $390,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Macromolecular and Materials Chemistry | Synthesis of Materials | Biomaterials | Nanochemistry and Supramolecular Chemistry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Plastics in Primary Forms |

Other Keywords

Biomaterials | Expanding Knowledge in the Chemical Sciences | Macromolecular and Materials Chemistry | Nanochemistry and Supramolecular Chemistry | Plastics in Primary Forms | Synthesis of Materials

Related Links