Discovery Projects - Grant ID: DP140103514

Funded Activity Summary

Toward sustainable diesel production using microbial cells: unravelling isoprenoid pathway regulation through systems biology. The methylerythritol pyrophosphate (MEP) pathway for isoprenoid production is an essential biochemical pathway. It was only fully elucidated a decade ago, and the regulatory controls over this pathway are not understood. The objective of this project is to elucidate the mechanisms by which the MEP pathway is controlled in E. coli using a novel systems biology approach. Understanding control of the MEP pathway is required to gain insight into homeostatic control of this essential pathway, and enable biotechnological engineering of E. coli in order to produce a wide range of industrially useful isoprenoids (including biofuels, pharmaceuticals, industrial chemicals, neutraceuticals, food additives, perfumes and many more).

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2017

Funding Scheme: Discovery Projects

Funding Amount: $376,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Industrial Microbiology (incl. Biofeedstocks) | Synthetic Biology | Systems Biology

ANZSRC Socio-Economic Objective (SEO)

Biofuel (Biomass) Energy | Organic Industrial Chemicals (excl. Resins, Rubber and Plastics) | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Biofuel (Biomass) Energy | Expanding Knowledge in the Biological Sciences | Industrial Microbiology (incl. Biofeedstocks) | Organic Industrial Chemicals (excl. Resins, Rubber and Plastics) | Synthetic Biology | Systems Biology

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