ARC Future Fellowships - Grant ID: FT130100142

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT130100142

Funding Status
Closed

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Funded Activity Summary

Overcoming antibiotic resistance: rapid discovery of new antibacterial drug targets using chemical proteomics. The prevalence of multidrug-resistant bacteria in the community is a critical public health issue and there is an urgent and compelling need for new antibiotics with novel modes of action to combat these deadly superbugs. While antibiotics from nature have long been a mainstay of the pharmaceutical industry, their development as drugs can be challenging as their cellular targets and modes of action are frequently unknown. In this project, innovative chemical proteomics approaches will be used to rapidly identify and characterise the cellular targets and modes of action of both newly discovered and historic antibiotic natural products, thereby overcoming this bottleneck and accelerating the development of next-generation antibiotics.

Funded Activity Details

Start Date: 07-04-2014

End Date: 30-06-2019

Funding Scheme: ARC Future Fellowships

Funding Amount: $752,788.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Medicinal and Biomolecular Chemistry | Biologically Active Molecules | Organic Chemistry not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Infectious Diseases |

Other Keywords

Biologically Active Molecules | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Infectious Diseases | Medicinal and Biomolecular Chemistry | Organic Chemistry not elsewhere classified | Proteomics and Intermolecular Interactions (excl. Medical Proteomics)

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