Extrasynaptic GABA-A receptors as novel targets for -Hydroxybutyric acid (GHB)

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1003619

Funding Status
Closed

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Funded Activity Summary

GHB (known as Fantasy) is a curious substance. It is a drug of abuse, a therapy and occurs naturally in the brain. GHB targets brain proteins including the enigmatic _GHB receptor� which participates in the therapeutic benefits of GHB. Our research will determine whether the delta-containing GABA-A receptors are the elusive "GHB receptor". Uncovering the identity of the the elusive _GHB receptor� would be a major breakthrough in terms of our understanding of the therapeutic and recreational use of GHB and its action as a brain chemical.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: NHMRC Project Grants

Funding Amount: $525,946.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

behavioural science | drug abuse | drug discovery | gamma-aminobutyric acid (GABA) receptors | neurotransmitters | pharmacology | sleep disorders | structure-function

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