Distinct pathogenic roles for JNK signalling in glomerular and interstitial injury in kidney disease.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1006348

Funding Status
Closed

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Funded Activity Summary

Our studies have identified a stress-activated mechanism (the JNK signalling pathway) as a therapeutic target in the treatment of kidney disease. The current project will define the role of JNK signaling in individual cell types in the development of different types of kidney disease. These studies will provide new insights into the pathogenesis of kidney disease, and will be highly relevant to other diseases, including atherosclerosis, lung fibrosis and arthritis.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $555,892.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

c-Jun/JNK kinase | diabetic nephropathy | experimental antiGBM glomerulonephritis | fibrosis | glomerular inflammation | glomerulosclerosis | immunopathology | kidney disease | renal interstitial fibrosis

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