Therapeutically exploiting non-oncogene addiction and defining genetic interactions for disease progression in a preclinical model of inflammation-dependent gastric tumourigenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1007523

Funding Status
Closed

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Funded Activity Summary

Cancers of the stomach are often associated with chronic inflammation and represent a major health burden with little treatment options available. We propose to test whether drugs undergoing clinical testing for other diseases may have beneficial effects in a preclinical model of gastric cancer, and establish the genetic interaction required for gastric cancer progression. The study outcomes may highlight novel therapeutic opportunities for the clinic.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $624,960.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cancer Cell Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

cancer | cancer genetics | cancer treatment | chronic inflammation | cytokine biology | gastric cancer | gastrointestinal tumourigenesis | inflammation | mouse models

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