PI3K-regulated heat shock proteins and microRNAs as new treatment strategies for atrial fibrillation

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008682

Funding Status
Closed

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Funded Activity Summary

Atrial fibrillation (AF) is the most common sustained arrhythmia presenting in cardiology departments worldwide and is associated with increased mortality and morbidity. New treatment strategies are greatly needed. We have discovered that lower levels of a gene with protective properties in the heart causes AF in mice and is associated with AF in humans. This proposal will examine whether novel agents that target this gene can reduce or prevent AF.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $553,633.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cardiology (incl. Cardiovascular Diseases)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

atrial fibrillation | cardiovascular disease | heart failure | heat shock proteins | microrna | mouse models | targeted gene delivery

Related Links

ACN 633 798 857