Role of survival motor neuron deficiency in motor neuron disease

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1008910

Funding Status
Closed

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Funded Activity Summary

The aim of this proposal is to understand the earliest and central pathological events in motor neuron disease (MND). This is important for drug development because therapies that target the early disease stages are likely to be effective. Our previous studies suggest that a protein essential for nerve cells, survival motor neuron, is lacking in MND. We will therefore examine how early this deficiency starts in disease and whether its replacement is beneficial. These outcomes may aid future studies to design new treatments for MND.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: NHMRC Project Grants

Funding Amount: $531,743.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

amyotrophic lateral sclerosis | motor neuron disease (MND) | neurobiology | neurochemistry | neurodegenerative disorders

Related Links

ACN 633 798 857