Lamstatin- a novel inhibitor of lymphangiogenesis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1009156

Funding Status
Closed

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Funded Activity Summary

We have discovered that part of a collagen molecule - lamstatin- inhibits growth of lymphatic cells and their communicating networks. Excessive lymphatic growth occurs in lymphangioleiomyomatosis (LAM)- a fatal disease which affects young women- and many cancers. We have shown that lamstatin prevents growth of lymph vessels in a skin tumour in mice and we will investigate if it can prevent spread of tumours to other organs which has exciting implications for the treatment of cancer.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $659,494.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Respiratory Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

airway remodelling | dissemination | lung cancer | lung disease | lymphangiogenesis | lymphatic disease | metastasis suppressor

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