Does a Novel Estrogen Receptor Worsen Stroke Outcome?

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1010984

Funding Status
Closed

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Funded Activity Summary

This project will test whether a target protein for estrogen, called GPER, which is found in high levels in the brain, worsens stroke outcome. We will identify the key signalling pathways related to GPER in the brain after stroke and we hope to identify a new type of drug that could be used to treat stroke patients. It is possible that our work could at least partly explain why hormone replacement therapy can increase the risk of worsened outcome after stroke in women.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2013

Funding Scheme: NHMRC Project Grants

Funding Amount: $524,820.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

G protein-coupled receptors | brain | cardiovascular disease | cerebral ischaemia | cerebrovascular | neuronal cell death | oestrogen receptor | stroke

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