microRNAs and their processing complexes integrate erbB-2 and AR signaling pathways in prostate cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1011944

Funding Status
Closed

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Funded Activity Summary

Prostate cancer is the most common cancer in men and is dependent upon signaling from male hormones (androgens) for continued growth. We recently identified some novel small RNAs (intracellular messengers), called microRNAs, that are likely to play important roles in the growth of prostate cancer cells. This project will evaluate the functional role of these microRNAs in human prostate cancer, as well as some other proteins involved in microRNA processing and may provide the foundation for new avenues for therapeutic intervention.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $660,665.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Receptors and Membrane Biology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

carcinogenesis | gene regulation | microrna | nuclear receptors | prostate cancer | receptor tyrosine kinase (RTK) | signalling pathways

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