Mechanisms of T cell mediated injury in renal vasculitis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1017559

Funding Status
Closed

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Funded Activity Summary

Anti-MPO glomerulonephritis (GN) is an aggressive disease causing severe and permanent injury to kidneys. This disease is thought to be due to an immune-mediated response to a protein (MPO) in neutrophils (a type of white blood cell). There is some evidence that other immune cells, CD4+ T cells, may be important in this disease. Experiments using models of anti-MPO GN will aim to define the role and mechanisms by which CD4+ T cells cause inflammation in the kidney.

Funded Activity Details

Start Date: 01-01-2011

End Date: 01-01-2014

Funding Scheme: Postgraduate Scholarships

Funding Amount: $133,351.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nephrology and Urology

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

T cells | autoimmune disease | autoimmunity | gene knockout | glomerulonephritis

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