Role of epigenetic modifyers MBD2 and TET proteins in DNA methylation and demethylation in cancer

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1029584

Funding Status
Closed

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Funded Activity Summary

Cancer is a disease of both genetics and epigenetics, the cell machinery that controls how the DNA code is read. DNA methylation is one part of epigenetics but few studies have investigated how the loss of methylation contributes to cancer formation. We have exciting new data that implicates specific proteins in this process and, with this funding we will determine how these proteins affect gene regulation in cancer, potentially leading to novel cancer diagnosis and treatment strategies.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $722,068.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA methylation | cancer cell biology | chromatin structure | epigenetics | gene expression

Related Links

ACN 633 798 857