The AGE/RAGE pathway in chronic liver disease; a novel target for prevention and treatment

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1029990

Funding Status
Closed

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Funded Activity Summary

Cirrhosis of the liver due to non-alcoholic fatty liver disease, chronic hepatitis and other liver diseases is now a major cause of illness and death in Australia. This project will examine how advanced glycation end products (AGEs), compounds formed in the body and also derived from our diet, contributes to the progression of liver scarring in these diseases. We will study whether drugs targeting these compounds can be used to reduce liver scarring and prevent the development of cirrhosis.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $461,822.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and Health Sciences not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

fatty liver disease | hepatic cirrhosis | hepatic fibrosis | insulin resistance | nonalcoholic steatohepatitis | obesity | steatosis

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