The Role of Raptor and Rictor Signalling Pathways in Osteogenesis and Mesenchymal Stem Cell Fate Determination

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1030528

Funding Status
Closed

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Funded Activity Summary

Skeletal diseases associated with excessive bone loss and skeletal fragility, such as osteoporosis, affect 2.2 million Australians and cost our health system approximately $7.4 billion per annum. Studies from our laboratory suggest a critical role for the mTOR signalling pathway in bone development. Using transgenic animals and state-of-the-art techniques, we will investigate the role of mTOR in pre- and post-natal skeletal development. Results from these studies may provide novel approaches to treat age-related bone loss syndromes.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $562,742.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Development, Proliferation and Death

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

adipocytes | developmental biology | osteoblast | osteoporosis | stem cells

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