New Approaches for Gene Mapping in Osteoporosis

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1032571

Funding Status
Closed

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Funded Activity Summary

Osteoporosis is the commonest metabolic bone disease worldwide, and costs Australia >1% of GDP. It is a strongly inherited disease. We recently completed a genome-wide association study in 2000 postmenopausal women with either very high or very low bone density, and identified many genes contributing to BMD. The current study aims to use next-generation sequencing to study these women in greater genetic depth, aiming to identify more clearly the exact genetic determinants of bone mass.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2014

Funding Scheme: Project Grants

Funding Amount: $893,592.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Quantitative Genetics (incl. Disease and Trait Mapping Genetics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

association studies | bone mineral density | fracture risk | osteoporosis | polymorphism | population genetics | sequencing

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