NOX enzymes as mediators of inflammation-triggered neurodegeneration: modulating NOX enzymes as novel therapies

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1037879

Funding Status
Closed

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Funded Activity Summary

The NEURINOX project aims at identifying novel therapeutic targets for neurodegenerative diseases; an increasing health issue for the ageing Australian population. NADPH oxidases (NOX) enzymes, generate reactive oxygen species, and are key regulators of neuroinflammation. Inflammatory dysregulation is characterized by a change in NOX activity. NEURINOX will expound the links between neuroinflammation, NOX enzyme activity & neurodegenerative diseases to identify novel therapeutic targets to treat neuroinflammation.

Funded Activity Details

Start Date: 01-01-2012

End Date: 01-01-2017

Funding Scheme: Targeted Calls

Funding Amount: $994,846.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurology and Neuromuscular Diseases

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

Parkinson disease | amyotrophic lateral sclerosis | autoimmune disease | enzymes | multiple sclerosis (MS) | neurodegenerative disorders | neuroinflammatory disease | neuropharmacology | oxidative stress | proteomics

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