Mechanisms of respiratory virus induced pneumococcal infection in the middle ear.

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1044976

Funding Status
Closed

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Funded Activity Summary

Streptococcus pneumoniae (the pneumococcus) is a common bacterium that temporarily lives in the nose of most young children, usually not causing any disease. Predisposing conditions, such as infection with a respiratory virus, may result in development of clinical disease. We will investigate how influenza virus mediates inflammation of the middle ear (otitis media) leading to pneumococcal infection. In particular, modulation of the middle ear innate immune response by viral protein will be studied.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $646,304.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Microbiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

infectious diseases | influenza virus | innate immunity | otitis media | pneumococcal disease

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