P2X7 mediated phagocytosis of apoptotic cells: a common mechanism underlies neurological and eye disorders

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1048082

Funding Status
Closed

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Funded Activity Summary

We have found a strong genetic linkage between a protein called P2X7 and a number of neurological disorders, in line with our recent discovery of a novel function of this protein in clearance of dying cells as removal of unhealthy neurons is essential to keep brain function promptly. Further study using genetic association, cell biology and animal models will lead to a conceptual advance on how neurological diseases are occurred and developed.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $527,033.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Neurogenetics

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

apoptosis of neurons | genetic association | neurodegenerative disorders | neurogenetics | phagocytosis

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