Early detection of chemotherapy-related cardiotoxicity

Funding Activity

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Funded Activity Summary

This project examines myocardial dysfunction in breast cancer patients treated with anthracycline chemotherapy. Chemotherapy related cardiotoxicity is often asymptomatic until significant cardiac dysfunction occurs. Cardiac function is evaluated by LV ejection fraction (LVEF), which is a coarse measure of cardiac function. Strain analysis measure myocardial deformation and is more sensitive to subclinical cardiac dysfunction, and demonstrates alterations prior to the development of reduced LVEF.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $269,401.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

ANZSRC Socio-Economic Objective (SEO)

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Other Keywords

biomarkers | breast cancer | cardiac dysfunction | chemotherapy treatment effects | echocardiography | magnetic resonance imaging (MRI)