New role for the E3 ligase E6AP in the control of cell motility and invasion

Funding Activity

Website
http://purl.org/au-research/grants/nhmrc/1049179

Funding Status
Closed

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Funded Activity Summary

Cell motility and invasion are fundamental process in normal cellular functions, however, when deregulated they can lead to metastatic cancer, a leading cause of cancer mortality and morbidity worldwide. Detailed understanding of the mechanisms governing these processes is essential for the development of new targets to prevent metastatic cancer. We discovered a protein that control these processes, which renders it an important target to investigate.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2015

Funding Scheme: Project Grants

Funding Amount: $462,162.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

actin cytoskeleton | breast cancer | cell motility | protein degradation | tumour invasion | tumour metastases

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