BEYOND TRADITIONAL GENE BOUNDARIES: Establishing the importance of enhancer epigenetic reprogramming and atypical long-range interactions in cancer cells.

Funding Activity

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Funded Activity Summary

Effective prevention and treatment strategies for cancer are still needed to combat this disease. By determining how DNA is packaged differently in prostate cancer cells relative to normal prostate cells, will allow us to understand how the specific location of regulatory centres or factories affects gene behavior. Unlike genetic defects in cancer, physical and chemical modifications to DNA in these centres are potentially reversible, providing an opportunity to develop novel therapeutics and diagnostic tools.

Funded Activity Details

Start Date: 01-01-2013

End Date: 01-01-2016

Funding Scheme: Project Grants

Funding Amount: $718,515.00

Funder: National Health and Medical Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics)

ANZSRC Socio-Economic Objective (SEO)

There are no SEO codes available for this funding activity

Other Keywords

DNA methylation | cancer cell biology | chromatin structure | enhancer | epigenetics | gene expression | prostate cancer

ACN 633 798 857